Results 11 to 20 of about 394,231 (262)
DeepDist: real-value inter-residue distance prediction with deep residual convolutional network
BMC Bioinformatics, 2021 Background Driven by deep learning, inter-residue contact/distance prediction has been significantly improved and substantially enhanced ab initio protein structure prediction.
Tianqi Wu +3 more
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Non-H3 CDR template selection in antibody modeling through machine learning [PDF]
PeerJ, 2019 Antibodies are proteins generated by the adaptive immune system to recognize and counteract a plethora of pathogens through specific binding. This adaptive binding is mediated by structural diversity in the six complementary determining region (CDR ...
Xiyao Long +2 more
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Water in protein structure prediction [PDF]
Proceedings of the National Academy of Sciences, 2004 Proteins have evolved to use water to help guide folding. A physically motivated, nonpairwise-additive model of water-mediated interactions added to a protein structure prediction Hamiltonian yields marked improvement in the quality of structure prediction for larger proteins.
Papoian, G A +4 more
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FALCON2: a web server for high-quality prediction of protein tertiary structures
BMC Bioinformatics, 2021 Background Accurate prediction of protein tertiary structures is highly desired as the knowledge of protein structures provides invaluable insights into protein functions.
Lupeng Kong +4 more
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CirPred, the first structure modeling and linker design system for circularly permuted proteins
BMC Bioinformatics, 2021 Background This work aims to help develop new protein engineering techniques based on a structural rearrangement phenomenon called circular permutation (CP), equivalent to connecting the native termini of a protein followed by creating new termini at ...
Teng-Ruei Chen +4 more
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Prediction of protein structure [PDF]
Current Biology, 2000 Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ: Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.Nucleic Acids Res 1997, 25:3389-3402Bowie JU, Eisenberg D: Inverted protein structure prediction.
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CASP11--An Evaluation of a Modular BCL::Fold-Based Protein Structure Prediction Pipeline. [PDF]
PLoS ONE, 2016 In silico prediction of a protein's tertiary structure remains an unsolved problem. The community-wide Critical Assessment of Protein Structure Prediction (CASP) experiment provides a double-blind study to evaluate improvements in protein structure ...
Axel W Fischer +7 more
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(PS)2-v2: template-based protein structure prediction server
BMC Bioinformatics, 2009 Background Template selection and target-template alignment are critical steps for template-based modeling (TBM) methods. To identify the template for the twilight zone of 15~25% sequence similarity between targets and templates is still difficulty for ...
Hwang Jenn-Kang +2 more
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Frontiers in Bioengineering and Biotechnology, 2022 Prediction of the protein secondary structure is a key issue in protein science. Protein secondary structure prediction (PSSP) aims to construct a function that can map the amino acid sequence into the secondary structure so that the protein secondary ...
Xin Jin +9 more
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Protein structure prediction in genomics [PDF]
Briefings in Bioinformatics, 2001 As the number of completely sequenced genomes rapidly increases, including now the complete Human Genome sequence, the post-genomic problems of genome-scale protein structure determination and the issue of gene function identification become ever more pressing.
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