Results 31 to 40 of about 410,461 (311)
(PS)2-v2: template-based protein structure prediction server
BMC Bioinformatics, 2009 Background Template selection and target-template alignment are critical steps for template-based modeling (TBM) methods. To identify the template for the twilight zone of 15~25% sequence similarity between targets and templates is still difficulty for ...
Hwang Jenn-Kang +2 more
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An artificial immune system for clustering amino acids in the context of protein function classification [PDF]
, 2009 This paper addresses the classification task of data mining (a form of supervised learning) in the context of an important bioinformatics problem, namely the prediction of protein functions.
Timmis, Jon +5 more
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Frontiers in Bioengineering and Biotechnology, 2022 Prediction of the protein secondary structure is a key issue in protein science. Protein secondary structure prediction (PSSP) aims to construct a function that can map the amino acid sequence into the secondary structure so that the protein secondary ...
Xin Jin +9 more
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Protein structure prediction in genomics [PDF]
Briefings in Bioinformatics, 2001 As the number of completely sequenced genomes rapidly increases, including now the complete Human Genome sequence, the post-genomic problems of genome-scale protein structure determination and the issue of gene function identification become ever more pressing.
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Sisyphus and prediction of protein structure [PDF]
Bioinformatics, 1997 The problem of predicting protein structure from the sequence remains fundamentally unsolved despite more than three decades of intensive research effort. However, new and promising methods in three-dimensional (3D), 2D and 1D prediction have reopened the field.
Burkhard Rost, Seán I. O'Donoghue
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FLORA: a novel method to predict protein function from structure in diverse superfamilies [PDF]
, 2009 Predicting protein function from structure remains an active area of interest, particularly for the structural genomics initiatives where a substantial number of structures are initially solved with little or no functional characterisation.
Dallman Timothy J. +24 more
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Advances in protein tertiary structure prediction
Biomedical and Biotechnology Research Journal, 2018 Proteins are composed of linear chains of amino acids that form a unique three-dimensional structure in their native environment. Such native structure favors the proteins to perform their biochemical activity.
Tayebeh Farhadi
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BMC Bioinformatics, 2020 Background Whenever suitable template structures are not available, usage of fragment-based protein structure prediction becomes the only practical alternative as pure ab initio techniques require massive computational resources even for very small ...
Jad Abbass, Jean-Christophe Nebel
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Progress in protein structure prediction? [PDF]
Trends in Biochemical Sciences, 1993 Prediction of protein secondary structure is an old problem and progress has been slow. Recently, spectacular success has been claimed in the blind prediction of the catalytic subunit of the cAMP-dependent protein kinase. When predictions in this and other test cases are assessed critically, some claims of prediction success turn out to be exaggerated,
ROST, B. +2 more
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An empirical evaluation of the effectiveness of different types of predictor attributes in protein function prediction. [PDF]
, 2009 Many classification schemes for defining protein functions, such as Gene Ontology (GO), are organised in a hierarchical structure. Nodes near the root of the hierarchy represent general functions while nodes near the leaves of the hierarchy represent ...
Segond, Marc +11 more
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