Results 231 to 240 of about 8,136,725 (292)

A high-resolution data set of fatty acid-binding protein structures. I. Dynamics of FABP4 and ligand binding. [PDF]

open access: yesActa Crystallogr D Struct Biol
Casagrande F   +5 more
europepmc   +1 more source

Structure of Proteins

Journal of the Society of Dyers and Colourists, 1939
THE structure of proteins is the major unsolved problem on the boundary of chemistry and biology to-day. We have not yet found the key to the problem, but in recent years a mass of new evidence and new lines of attack have enabled us to see it in a far more concrete and precise form, and to have some hope that we are near to solving it.
openaire   +1 more source

Protein Structure Prediction and Structural Genomics

Science, 2001
Genome sequencing projects are producing linear amino acid sequences, but full understanding of the biological role of these proteins will require knowledge of their structure and function. Although experimental structure determination methods are providing high-resolution structure information about a subset of the proteins, computational structure ...
D, Baker, A, Sali
openaire   +2 more sources

Protein Structure Prediction

2008
Protein structure prediction has matured over the past few years to the point that even fully automated methods can provide reasonably accurate three-dimensional models of protein structures. However, until now it has not been possible to develop programs able to perform as well as human experts, who are still capable of systematically producing better
AlLazikani B, Hill EE, Morea V
openaire   +4 more sources

Protein structure

2016
This chapter explores the structures of proteins in more detail than thus far in this text. Building on the basic structural and physical chemistry of amino acids and protein conformations, it examines the features that stabilize native states. Proteins combine the unity of a common and repetitive mainchain with the variety available from a sequence of
openaire   +1 more source

The structure of protein evolution and the evolution of protein structure

Current Opinion in Structural Biology, 2008
The observed distribution of protein structures can give us important clues about the underlying evolutionary process, imposing important constraints on possible models. The availability of results from an increasing number of genome projects has made the development of these models an active area of research.
openaire   +2 more sources

Protein Structure Databases

Molecular Biotechnology, 2009
Web-based protein structure databases come in a wide variety of types and levels of information content. Those having the most general interest are the various atlases that describe each experimentally determined protein structure and provide useful links, analyses, and schematic diagrams relating to its 3D structure and biological function.
openaire   +4 more sources

Protein structure prediction

Current Opinion in Chemical Biology, 2001
The prediction of protein structure, based primarily on sequence and structure homology, has become an increasingly important activity. Homology models have become more accurate and their range of applicability has increased. Progress has come, in part, from the flood of sequence and structure information that has appeared over the past few years, and ...
B, Al-Lazikani   +3 more
openaire   +2 more sources

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