Results 41 to 50 of about 1,322,999 (349)

A Subunit Vaccine Based on E2 Protein of Atypical Porcine Pestivirus Induces Th2-type Immune Response in Mice

Viruses, 2018
An atypical porcine pestivirus (APPV) causing congenital tremor type A-II in piglets was identified in China in 2016. An increased number of cases of APPV have been reported in various countries all over the world since 2015.
Huawei Zhang, Wei Wen, Genxi Hao, Huanchun Chen, Ping Qian, Xiangmin Li   +5 more
doaj   +1 more source

ISOLATION OF A PROTEIN SUBUNIT FROM MICROTUBULES [PDF]

The Journal of Cell Biology, 1967
Sea-urchin sperm tails (Strongylocentrotus purpuratus) were obtained by amputation in synthetic sea water and were purified by differential centrifugation. Most of the arms of the outer nine doublets and soluble matrix proteins were removed by this treatment. The central pairs of microtubules were dissolved by dialysis against EDTA at pH 7.5.
Edwin W. Taylor, M. L. Shelanski
openaire   +3 more sources

Protein Kinase A Regulatory Subunits in Colon Cancer

Neoplasia: An International Journal for Oncology Research, 1999
The protein kinase A (PKA) is classified as type I or II depending on the association of the catalytic subunit with either the RI or RII regulatory subunits.
Chris C. Carlson, Stacy L. Smithers, Karen A. Yeh, Laura L. Burnham, Daniel T. Dransfield   +4 more
doaj   +1 more source

Generation of active protein phosphatase 2A is coupled to holoenzyme assembly. [PDF]

PLoS Biology, 2007
Protein phosphatase 2A (PP2A) is a prime example of the multisubunit architecture of protein serine/threonine phosphatases. Until substrate-specific PP2A holoenzymes assemble, a constitutively active, but nonspecific, catalytic C subunit would constitute
Hans Hombauer, David Weismann, Ingrid Mudrak, Claudia Stanzel, Thomas Fellner, Daniel H Lackner, Egon Ogris   +6 more
doaj   +1 more source

Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire [PDF]

, 2012
Idiosyncratic adverse drug reactions are unpredictable, dose independent and potentially life threatening; this makes them a major factor contributing to the cost and uncertainty of drug development. Clinical data suggest that many such reactions involve
A. Lucas, A. M. English, A. Sette, A. Wriston, B. J. Grant, B. Peters, C. A. F. de Oliveira, C. Oseroff, Cahalan, Chessman, Chung, D. A. Ostrov, D. F. Hunt, Day, E. Phillips, Faletto, Friesner, H. M. Grey, H. Mei, Harndahl, J. Jakoncic, J. Shabanowitz, J. Sidney, Ko, L. Shi, L. Yang, Lavergne, M. Harndahl, Mallal, Martin, Melroy, Phillips, Pichler, Rudolph, S. Buus, S. Lu, S. Mallal, S. Southwood, Shastri, Shimizu, Sidney, Sidney, Tenzer, Udeshi, Y. A. Pompeu, Yang, Yang, Yewdell   +47 more
core   +4 more sources

Bioenergetic Consequences of FLAG Tag Addition to the C-Terminus of Subunit 8 of Yeast Saccharomyces cerevisiae Mitochondrial ATP Synthase

Hayati Journal of Biosciences, 2010
The yeast mitochondrial F1F0-ATP synthase is a multisubunit complex that contains at least 17 different subunits. Subunit 8 of yeast mitochondrial ATP synthase is a hydrophobic protein of 48 amino acids encoded by the mitochondrial ATP8 gene.
I MADE ARTIKA
doaj   +3 more sources

Idiosyncratic evolution of conserved eukaryote proteins that are similar in sequence to archaeal or bacterial proteins [PDF]

, 2008
Sequence comparisons have been made between the proteins of 571 prokaryote species including 46 archaea and 525 bacteria and the set of human proteins.
Roy J. Britten
core   +2 more sources

Analytical Insights into Protein–Alum Interactions and Their Impact on Conformational Epitope

Pharmaceutics
Several alum-adjuvanted vaccines have been licensed in the past 40 years. Despite its extensive and continuous use, the immune mechanism of action of alum adjuvants is not yet completely understood. Many different variables during the formulation process
Alessio Corrado, Mila Toppazzini, Alessandro Vadi, Carmine Malzone, Rosy Galasso, Alessandro Donati, Riccardo De Ricco, Francesco Berti   +7 more
doaj   +1 more source

Epigallocatechin gallate restores the reduction of protein phosphatase 2 A subunit B caused by middle cerebral artery occlusion

Laboratory Animal Research, 2023
Background Epigallocatechin gallate (EGCG) is a flavonoid compound commonly found in green tea. It exhibits antioxidant, anti-inflammatory, and neuroprotective effects in cerebral ischemia.
Murad-Ali Shah, Ju-Bin Kang, Dong-Ju Park, Phil Ok Koh   +3 more
doaj   +1 more source

Identification of key genes for hypertrophic cardiomyopathy using integrated network analysis of differential lncRNA and gene expression

Frontiers in Cardiovascular Medicine, 2022
ObjectiveHypertrophic cardiomyopathy (HCM) is a complex heterogeneous heart disease. Recent reports found that long non-coding RNAs (lncRNAs) play an important role in the progression of cardiovascular diseases.
Jing Cao, Lei Yuan
doaj   +1 more source