Results 41 to 50 of about 1,344,747 (350)

Picosecond time-resolved fluorescence of phycobiliproteins [PDF]

, 1990
The α- and β-subunits of C-phycocyanin from Mastigocladus laminosus were prepared according to revised procedures. Both subunits are isolated as dimers, which can be dissociated into monomers with detergent mixtures.
Bryant, Bryant, Burke, Castenholz, Fischer, Füglistaller, Gantt, Geiselhart, Glazer, Glazer, Grabowski, H. Scheer, Hefferle, Holzwarth, J. Gottstein, Kufer, Köhler, Köhler, Köst-Reyes, Lundell, MacColl, Martin, Mimuro, Mimuro, P. Geiselhart, R. Fischer, Rümbeli, S. Schneider, Sandström, Sauer, Scharnagl, Scheer, Scheer, Scheer, Scheer, Scheer, Scheer, Schirmer, Schirmer, Schmidt, Schneider, Siebzehnrübl, Siebzehnrübl, Switalsky, Teale, Wehrmeyer, Zuber   +46 more
core   +1 more source

Analytical Insights into Protein–Alum Interactions and Their Impact on Conformational Epitope

Pharmaceutics
Several alum-adjuvanted vaccines have been licensed in the past 40 years. Despite its extensive and continuous use, the immune mechanism of action of alum adjuvants is not yet completely understood. Many different variables during the formulation process
Alessio Corrado, Mila Toppazzini, Alessandro Vadi, Carmine Malzone, Rosy Galasso, Alessandro Donati, Riccardo De Ricco, Francesco Berti   +7 more
doaj   +1 more source

Epigallocatechin gallate restores the reduction of protein phosphatase 2 A subunit B caused by middle cerebral artery occlusion

Laboratory Animal Research, 2023
Background Epigallocatechin gallate (EGCG) is a flavonoid compound commonly found in green tea. It exhibits antioxidant, anti-inflammatory, and neuroprotective effects in cerebral ischemia.
Murad-Ali Shah, Ju-Bin Kang, Dong-Ju Park, Phil Ok Koh   +3 more
doaj   +1 more source

A Mammalian Mediator Subunit that Shares Properties with Saccharomyces cerevisiae Mediator Subunit Cse2 [PDF]

, 2004
The multiprotein Mediator complex is a coactivator required for activation of RNA polymerase II transcription by DNA bound transcription factors. We previously identified and partially purified a mammalian Mediator complex from rat liver nuclei (Brower ...
Banks, Charles A. S., Brower, Christopher S., Conaway, Joan Weliky, Conaway, Ronald C., Florens, Laurence, Parmely, Tari J., Sato, Shigeo, Sorokina, Irina, Tomomori-Sato, Chieri, Washburn, Michael P., Zybailov, Boris   +10 more
core   +1 more source

Identification of key genes for hypertrophic cardiomyopathy using integrated network analysis of differential lncRNA and gene expression

Frontiers in Cardiovascular Medicine, 2022
ObjectiveHypertrophic cardiomyopathy (HCM) is a complex heterogeneous heart disease. Recent reports found that long non-coding RNAs (lncRNAs) play an important role in the progression of cardiovascular diseases.
Jing Cao, Lei Yuan
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

TRAF2 Is a Novel Ubiquitin E3 Ligase for the Na,K-ATPase β-Subunit That Drives Alveolar Epithelial Dysfunction in Hypercapnia

Frontiers in Cell and Developmental Biology, 2021
Several acute and chronic lung diseases are associated with alveolar hypoventilation leading to accumulation of CO2 (hypercapnia). The β-subunit of the Na,K-ATPase plays a pivotal role in maintaining epithelial integrity by functioning as a cell adhesion
Nieves M. Gabrielli, Luciana C. Mazzocchi, Vitalii Kryvenko, Vitalii Kryvenko, Khodr Tello, Khodr Tello, Susanne Herold, Susanne Herold, Rory E. Morty, Rory E. Morty, Rory E. Morty, Friedrich Grimminger, Friedrich Grimminger, Friedrich Grimminger, Laura A. Dada, Werner Seeger, Werner Seeger, Werner Seeger, Werner Seeger, Jacob I. Sznajder, István Vadász, István Vadász   +21 more
doaj   +1 more source

Mitochondrial ribosome assembly in Neurospora. Structural analysis of mature and partially assembled ribosomal subunits by equilibrium centrifugation in CsCl gradients [PDF]

, 1982
In Neurospora, one protein associated with the mitochondrial small ribosomal subunit (S-5, Mr 52,000) is synthesized intramitochondrially and is assumed to be encoded by mtDNA.
Lambowitz, Alan M., LaPolla, Robert J.
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Structures and proton-pumping strategies of mitochondrial respiratory enzymes [PDF]

, 2001
Enzymes of the mitochondrial respiratory chain serve as proton pumps, using the energy made available from electron transfer reactions to transport protons across the inner mitochondrial membrane and create an electrochemical gradient used for the ...
Chan, Sunney I., Schultz, Brian E.
core   +1 more source