Results 241 to 250 of about 723,610 (311)

Highly Sensitive Detection of Human Serum Albumin Biomarker Using a Molecularly Imprinted Polymer‐Based Electrochemical Capacitance Sensor

open access: yesAdvanced Sensor Research, EarlyView.
An electrosynthesized protein‐imprinted polymer (poly(azo‐BBY)) enables probe‐free, real‐capacitance detection of human serum albumin at 0.02 ng mL−1 within a 0.25–3.0 ng mL−1 window. The device uses a redox‐mediator‐free architecture and maintains selectivity against common interferents, illustrating a simple, scalable route to high‐sensitivity ...
Heitor F. Trevizan   +4 more
wiley   +1 more source

N3A motifs in RIβ mediate allosteric crosstalk between cAMP and ATP in PKA activation. [PDF]

open access: yesProtein Sci
Wu J   +6 more
europepmc   +1 more source

Gallium β‐Cyclodextrin Nanoparticles Containing both Gallium Protoporphyrin and Gallium Nitrate Exhibit Antimicrobial Activity against Nontuberculous Mycobacteria in Vitro and in Vivo

open access: yesAdvanced Therapeutics, EarlyView.
Cyclodextrin nanoparticle containing both Ga(NO3)3 and GaPP is synthesized and tested against non‐tuberculous mycobacteria (NTM). The in vivo efficacy of the nanoparticle therapy is additionally tested by treating pulmonary NTM infections in mice and observed much greater effectiveness in bacterial clearance and survival of mice.
Seoung‐ryoung Choi   +2 more
wiley   +1 more source

Structural characterization of an extracellular contractile injection system from Photorhabdus luminescens in extended and contracted states. [PDF]

open access: yesNat Commun
Marín-Arraiza L   +7 more
europepmc   +1 more source

LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing

open access: yesAdvanced Science, EarlyView.
This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang   +15 more
wiley   +1 more source

Properties of Heterochannels Kv(1.1-1.2)<sub>2</sub> with Mutation T226R in the Kv1.1 Subunit. [PDF]

open access: yesInt J Mol Sci
Ignatova AA   +7 more
europepmc   +1 more source

Excessive DNA Double‐Strand Breaks–Associated 3D Genome Reorganization Contributes to Neural Tube Defects with Folate Deficiency

open access: yesAdvanced Science, EarlyView.
Neural tube defects (NTDs) are among the most common congenital malformations. However, the underlying etiology and mechanism remain elusive. Here, the role of DNA double‐strand breaks (DSBs) in 3D genome organization within the NTDs with folate deficiency is reported.
Ting Zhang   +12 more
wiley   +1 more source

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