Results 41 to 50 of about 11,322,924 (398)

Gene duplication and an accelerated evolutionary rate in 11S globulin genes are associated with higher protein synthesis in dicots as compared to monocots [PDF]

, 2012
Background: Seed storage proteins are a major source of dietary protein, and the content of such proteins determines both the quantity and quality of crop yield.
Dunwell, Jim, Li, Chun, Li, Meng, Zhang, Yuan-Ming   +3 more
core   +2 more sources

Stem cell function and stress response are controlled by protein synthesis

Nature, 2016
Whether protein synthesis and cellular stress response pathways interact to control stem cell function is currently unknown. Here we show that mouse skin stem cells synthesize less protein than their immediate progenitors in vivo, even when forced to ...
S. Blanco, R. Bandiera, Martyna C Popis, S. Hussain, P. Lombard, J. Aleksić, Abdulrahim A. Sajini, H. Tanna, Rosana Cortés-Garrido, Nikoletta A Gkatza, S. Dietmann, M. Frye   +11 more
semanticscholar   +1 more source

RETRACTED ARTICLE: Functionalized graphene oxide nanosheets with folic acid and silk fibroin as a novel nanobiocomposite for biomedical applications

Scientific Reports, 2022
In this paper, a novel graphene oxide-folic acid/silk fibroin (GO-FA/SF) nanobiocomposite scaffold was designed and fabricated using affordable and non-toxic materials.
Reza Eivazzadeh-Keihan, Farkhondeh Alimirzaloo, Hooman Aghamirza Moghim Aliabadi, Ehsan Bahojb Noruzi, Ali Reza Akbarzadeh, Ali Maleki, Hamid Madanchi, Mohammad Mahdavi   +7 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Transcriptome-wide analysis of the function of Ded1 in translation preinitiation complex assembly in a reconstituted in vitro system

eLife
We have developed a deep sequencing-based approach, Rec-Seq, that allows simultaneous monitoring of ribosomal 48S preinitiation complex (PIC) formation on every mRNA in the translatome in an in vitro reconstituted system. Rec-Seq isolates key early steps
Fujun Zhou, Julie M Bocetti, Meizhen Hou, Daoming Qin, Alan G Hinnebusch, Jon R Lorsch   +5 more
doaj   +1 more source

Temperature-dependent regulation of upstream open reading frame translation in S. cerevisiae

BMC Biology, 2019
Background Translation of an mRNA in eukaryotes starts at an AUG codon in most cases, but near-cognate codons (NCCs) such as UUG, ACG, and AUU can also be used as start sites at low levels in Saccharomyces cerevisiae.
Shardul D. Kulkarni, Fujun Zhou, Neelam Dabas Sen, Hongen Zhang, Alan G. Hinnebusch, Jon R. Lorsch   +5 more
doaj   +1 more source

Inter-residue through-space scalar ¹⁹F–¹⁹F couplings between CH₂F groups in a protein [PDF]

Magnetic Resonance
Using cell-free protein synthesis, the protein G B1 domain (GB1) was prepared with uniform high-level substitution of leucine by (2S,4S)-5-fluoroleucine (FLeu1), (2S,4R)-5-fluoroleucine (FLeu2), or 5,5′-difluoroleucine (diFLeu).
Y. J. Tan, E. H. Abdelkader, I. D. Herath, A. Maleckis, G. Otting   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A spatial analysis of physiological changes associated with infection of cotyledons of marrow plants with cucumber mosaic virus [PDF]

, 1996
Changes in host primary metabolism associated with the compatible interaction between cucumber mosaic virus and cotyledons of the marrow plant (Cucurbita pepo L.) have been localized, first by measuring activities of key enzymes in infected and ...
Leegood, R.C., Maule, A.J., Smith, A.M., Tecsi, L.I.   +3 more
core   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source