Results 171 to 180 of about 1,981,418 (307)

Expanded genetic alphabet increases structural and chemical diversity of six-letter DNA for high-affinity protein-targeting aptamers. [PDF]

Nat Commun
Sawada K, Kimoto M, Matsunaga KI, Tan HP, Takayanagi R, Sano FK, Shuto Y, Hirano H, Kusakizako T, Itoh Y, Kise Y, Hirao I, Nureki O.   +12 more
europepmc   +1 more source

Protein Targeting

Bioscience Reports, 2000
openaire   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

ASAFind 2.0: multi-class protein targeting prediction for diatoms and algae with complex plastids. [PDF]

Plant J
Gruber A, Vohnoutová M, McKay C, Rocap G, Oborník M.   +4 more
europepmc   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Identification and antiviral mechanism of a novel chicken-derived interferon-related antiviral protein targeting PRDX1. [PDF]

PLoS Pathog
Chen J, Li P, Li L, Li J, Jiang Y, Zou W, Hao P, Gao Z, Hao J, Shi X, Fei D, Ma M, Wang G, Li C.   +13 more
europepmc   +1 more source

Stepwise protein targeting into plastoglobules are facilitated by three hydrophobic regions of rice phytoene synthase 2. [PDF]

Front Plant Sci, 2023
Yu JS, You MK, Lee YJ, Ha SH.
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Fibroblast activation protein targeting radiopharmaceuticals: From drug design to clinical translation. [PDF]

Acta Pharm Sin B
Wu Y, Wang X, Sun X, Gao X, Zhang S, Shen J, Tian H, Chen X, Huang H, Jiang S, Zhang B, Zhang Y, Lu M, Zhang H, Sun Z, Liu R, Zhang H, Zhang MR, Hu K, Wang R.   +19 more
europepmc   +1 more source

RecF protein targeting to postreplication (daughter strand) gaps I: DNA binding by RecF and RecFR. [PDF]

Nucleic Acids Res, 2023
Henry C, Mbele N, Cox MM.
europepmc   +1 more source