Results 61 to 70 of about 9,037,048 (379)
Drive, filter, and stick: A protein sorting conspiracy in photoreceptors. [PDF]
The sorting of proteins into different functional compartments is a fundamental cellular task. In this issue, Maza et al. (2019. J. Cell Biol https://doi.org/10.1083/jcb.201906024) demonstrate that distinct protein populations are dynamically generated ...
Aidan I. Brown+12 more
core +1 more source
CLC transport proteins in plants [PDF]
Other CLC homologues have been cloned in Arabidopsis, tobacco, rice and soybean.
Zifarelli G, Pusch M
openaire +5 more sources
In vivo experiments do not support the charge zipper model for Tat translocase assembly
The twin-arginine translocase (Tat) transports folded proteins across the bacterial cytoplasmic membrane and the plant thylakoid membrane. The Tat translocation site is formed by substrate-triggered oligomerization of the protein TatA.
Felicity Alcock+3 more
doaj +1 more source
Escherichia coli TatA and TatB Proteins Have N-out, C-in Topology in Intact Cells [PDF]
The twin arginine protein transport (Tat) system translocates folded proteins across the cytoplasmic membrane of prokaryotes and the thylakoid membrane of chloroplasts.
Alami+58 more
core +2 more sources
Dendritic cells steering antigen and leukocyte traffic in lymph nodes
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta+3 more
wiley +1 more source
Background Synthesis of the hemostatic protein von Willebrand factor (VWF) drives formation of endothelial storage organelles called Weibel‐Palade bodies (WPBs).
Maaike Schillemans+11 more
doaj +1 more source
Simple biophysics underpins collective conformations of the intrinsically disordered proteins of the Nuclear Pore Complex [PDF]
Nuclear Pore Complexes (NPCs) are key cellular transporter that control nucleocytoplasmic transport in eukaryotic cells, but its transport mechanism is still not understood.
Coalson, Rob D.+7 more
core +1 more source
Glioblastoma tumour cells release microvesicles (exosomes) containing mRNA, miRNA and angiogenic proteins. These microvesicles are taken up by normal host cells, such as brain microvascular endothelial cells.
J. Skog+9 more
semanticscholar +1 more source
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali+3 more
wiley +1 more source
Colistin- and carbapenem-resistant Acinetobacter baumannii is a serious multidrug resistant (MDR) bacterium in clinical settings. Discovery of new antibacterial drugs against MDR is facing multiple challenges in drug development.
Nalumon Thadtapong+4 more
doaj +1 more source