Results 121 to 130 of about 41,275 (256)

Pan-cancer analyses of classical protein tyrosine phosphatases and phosphatase-targeted therapy in cancer. [PDF]

Front Immunol, 2022
Wang T, Ba X, Zhang X, Zhang N, Wang G, Bai B, Li T, Zhao J, Zhao Y, Yu Y, Wang B.   +10 more
europepmc   +1 more source

N6‐Methyladenosine in Inflammatory Bowel Disease: An Emerging Regulator of Pathogenesis and a Novel Therapeutic Frontier

iMetaMed, EarlyView.
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine associated with an imbalance in intestinal homeostasis. m6A‐modifying enzymes, consisting of m6A writers, erasers and readers, plays a pivotal role in the pathogenesis and progression of IBD by affecting four intestinal barriers, including the intestinal mechanical ...
Jiaxian Guo, Yang Zhang, Xin Wang, Shan Cao, Jun Xu   +4 more
wiley   +1 more source

Protein Tyrosine Phosphatases in Schizophrenia: A Review of Pathophysiology and Emerging Evidence. [PDF]

Cureus
Murugesan K, Rebellow D, Kasagga A, Mon AM, Anwar S.   +4 more
europepmc   +1 more source

Protein Tyrosine Phosphatases: A new paradigm in an old signaling system? [PDF]

Adv Cancer Res, 2021
Welsh CL, Pandey P, Ahuja LG.
europepmc   +1 more source

Gut microbiota‐mediated immune and metabolic dysregulation in coronary artery disease progression and prognosis

iMeta, EarlyView.
The gut microbiota has emerged as a metabolically active endocrine‐like organ with a crucial role in coronary artery disease (CAD), yet its contribution to adverse clinical outcomes remains incompletely understood. In this prospective cohort of 319 participants, we integrated metagenomic and metabolomic profiling with longitudinal follow‐up over a ...
Honghong Liu, Siqin Feng, Lifeng Liang, Muyun Tang, Yifei Wang, Yiyang Wang, Zhiyu Zhang, Haiping Xing, Chenhong Zhang, Ran Tian, Shuyang Zhang   +10 more
wiley   +1 more source

Loop dynamics, allostery, and function in protein tyrosine phosphatases: insights from molecular simulations. [PDF]

Biochem Soc Trans
Welsh CL, Kamerlin SCL.
europepmc   +1 more source

Friend or foe? Unraveling the complex roles of protein tyrosine phosphatases in cardiac disease and development. [PDF]

Cell Signal, 2022
Krenz M.
europepmc   +1 more source

Maternal and infant gut microbiome

iMeta, EarlyView.
The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang, Felicia Tin, Hui Chen, Fuxin Jiao, Min Wu, Shanshan Sun, Lisha Lin, Die Li, Huimin Zheng, Zhenxin Niu, Mengyao Lan, Bahtiyar Yilmaz, Johan G. Eriksson, Mengjia Wang, Andrew Macpherson, Jose C. Clemente, Jia Xu, Ri‐hua Xie, Xiaojiao Zheng, Tao Zhou, Jinfeng Wang, Wei Shen, Bing Huang, Xia Chen, Hai Li, Yan He   +25 more
wiley   +1 more source

Orchestrating function: Concerted dynamics, allostery, and catalysis in protein tyrosine phosphatases. [PDF]

Curr Opin Struct Biol
Woods VA, Sharma S, Lemberikman AM, Keedy DA.   +3 more
europepmc   +1 more source

Protein tyrosine phosphatases in cell adhesion. [PDF]

Biochem J, 2021
Young KA, Biggins L, Sharpe HJ.
europepmc   +1 more source