Results 161 to 170 of about 306,745 (298)

A rapid and cost-effective Chelex-100 resin-based method for genomic DNA extraction from adult zebrafish tissues. [PDF]

PLoS One
Feng W, Li B, Niu Y, Xu Q, Zhai X.
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Plasma levels of human granulocytic elastase-alpha1-proteinase inhibitor complex (E-alpha1PI) in patients with septicemia and acute leukemia [PDF]

, 1983
Werner, M., Goldberg, D. M., Hiller, E., Jochum, Marianne, Fritz, Hans, Duswald, Karl-Heimo   +5 more
core   +1 more source

A multi-modal profiling workflow of transcriptomics and biomineralization demonstrated on a tooth-on-chip model. [PDF]

MethodsX
Huang C, Tijhof C, Ji W, Yang F, Walboomers XF.   +4 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Elastase-alpha1-proteinase inhibitor complex [PDF]

, 1984
Neumann, S., Bergmeyer, H. U., Graßl, M., Jochum, Marianne, Bergmeyer, J.   +4 more
core   +1 more source

QSAR-Based Ecotoxicological Assessment of Novel Imidazole Derivatives for Sustainable Crop Protection. [PDF]

Molecules
Kanižai Šarić G, Paurević M, Dandić A, Šrajer Gajdošik M, Rastija V.   +4 more
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Proteinase Inhibitors from Dog Submandibular Glands [PDF]

, 1971
Meister, Renate, Jaumann, Eugen, Fritz, Hans, Hochstrasser, Karl, Pasquay, Peter, Fink, Edwin   +5 more
core   +1 more source

Case Report: Serum Protein Electrophoresis Incidentally Reveals Alpha-1 Antitrypsin Deficiency in p-ANCA-Positive Crescentic Glomerulonephritis. [PDF]

Int J Rheum Dis
Komac A, Serin N, Karadag DT, Baris SA, Cefle A.   +4 more
europepmc   +1 more source