Results 121 to 130 of about 409,825 (329)

Exploring Frequencies of Circulating Specific Th17 Cells against Myeloperoxidase and Proteinase 3 in ANCA Associated Vasculitis [PDF]

, 2019
Laura Martínez Valenzuela, Juliana Draibe, María Quero, Xavier Fulladosa, Josep María Cruzado, Oriol Bestard, Joan Torrás   +6 more
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Specificity of anti-neutrophil cytoplasmic autoantibodies for proteinase 3 [letter; comment] [PDF]

, 1990
J. Charles Jennette, JR Hoidal, Ronald J. Falk   +2 more
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Proteinase 3 Antibody and Anti-Double-Stranded DNA in a Patient With Immunoglobin Light Chain Amyloidosis. [PDF]

Cureus, 2023
Cobb JK, Shiver L, Russell CR, Chen B, Bassil C.   +4 more
europepmc   +1 more source

Elastase, but not proteinase 3 (PR3), induces proteinuria associated with loss of glomerular basement membrane heparan sulphate after in vivo renal perfusion in rats [PDF]

, 1996
Peter Heeringa, Jacob van den Born, Elisabeth Brouwer, Koert M. Dolman, Pieter A. Klok, Minke G. Huitema, P. C. Limburg, Marinka A.H. Bakker, Jo H. M. Berden, Mohamed R. Daha, C. G. M. Kallenberg   +10 more
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Antineutrophil cytoplasmic antibodies in Chinese patients with tuberculosis

Revista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION: Based on reports, infection with Mycobacterium tuberculosis is believed to induce the development of antibodies that are considered to be biological indicators for the diagnosis of some other diseases.
Gao Huan, Gao Yang, Qu Xiao-yu, Xu Jiancheng, Song Yan-qing   +4 more
doaj   +1 more source

Clinical Validity of Anti-Proteinase 3 Antibodies in Patients with Inflammatory Bowel Disease: A Short Meta-Analysis. [PDF]

Diagnostics (Basel), 2023
Andalucía C, Martínez-Prat L, Bentow C, Aure MA, Horn MP, Mahler M.   +5 more
europepmc   +1 more source

Matrix Metalloproteinase-7 Facilitates Insulin-Like Growth Factor Bioavailability through Its Proteinase Activity on Insulin-Like Growth Factor Binding Protein 3 [PDF]

, 2004
Shin’ichi Miyamoto, Keiichi Yano, Seiji Sugimoto, Genichiro Ishii, Takahiro Hasebe, Yasushi Endoh, Keiji Kodama, Masato Goya, Tsutomu Chiba, Atsushi Ochiai   +9 more
openalex   +1 more source