Results 121 to 130 of about 357,202 (334)

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Antibodies to proteinase-3 and myeloperoxidase in systemic vasculitis

Терапевтический архив, 2004
Aim. To investigate occurrence and diagnostic significance of antibodies to proteinase-3 (aPR-3) and myeloperoxidase (aMPO) in systemic vasculitis (SV). Material and methods.
A A Baranov, S Yu Kirdyanov, T V Beketova, O V Bazhina, M S Guryeva, N E Abaitova   +5 more
doaj  

Biofilm Formation and Aspartyl Proteinase Activity and Their Association with Azole Resistance Among Candida albicans Causing Vulvovaginal Candidiasis, Egypt

Infection and Drug Resistance, 2023
Marian A Gerges,1 Yasmin Ahmed Fahmy,1 Thoraya Hosny,2 Nessma H Gandor,2 Sherif Y Mohammed,2 Tahia Mohamed Ahmed Mohamed,2 Nabila Elsayed Mousa Abdelmoteleb,3 Noura E Esmaeel1 1Medical Microbiology and Immunology Department, Faculty of Medicine, Zagazig ...
Gerges MA, Fahmy YA, Hosny T, Gandor NH, Mohammed SY, Mohamed TMA, Abdelmoteleb NEM, Esmaeel NE   +7 more
doaj  

Proteinase 3; a potential target in chronic obstructive pulmonary disease and other chronic inflammatory diseases

Respiratory Research, 2018
Chronic Obstructive Pulmonary Disease (COPD) is a common, multifactorial lung disease which results in significant impairment of patients’ health and a large impact on society and health care burden.
Helena Crisford, Elizabeth Sapey, Robert A. Stockley   +2 more
doaj   +1 more source

Proteinase 3 Antibody and Anti-Double-Stranded DNA in a Patient With Immunoglobin Light Chain Amyloidosis. [PDF]

Cureus, 2023
Cobb JK, Shiver L, Russell CR, Chen B, Bassil C.   +4 more
europepmc   +1 more source

Intramitochondrial sorting of the precursor to yeast cytochrome c oxidase subunit Va. [PDF]

, 1993
We have continued our studies on the import pathway of the precursor to yeast cytochrome c oxidase subunit Va (pVa), a mitochondrial inner membrane protein.
Cumsky, MG, Miller, BR
core  

Helical mutations in type I collagen that affect the processing of the amino-propeptide result in an Osteogenesis Imperfecta/Ehlers-Danlos Syndrome overlap syndrome [PDF]

, 2013
Background: Whereas mutations affecting the helical domain of type I procollagen classically cause Osteogenesis Imperfecta (OI), helical mutations near the amino (N)-proteinase cleavage site have been suggested to result in a mixed OI/Ehlers-Danlos ...
De Paepe, Anne, Goemans, Nathalie, Gyftodimou, Yolanda, Holmberg, Eva, Lopez-Gonzalez, Vanesa, Malfait, Fransiska, Mortier, Geert, Nampoothiri, Sheela, Petersen, Michael Bjorn, Symoens, Sofie   +9 more
core   +2 more sources

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

In vitro and in vivo anthelmintic efficacy of plant cysteine proteinases against the rodent gastrointestinal nematode, Trichuris muris [PDF]

, 2006
We examined the mechanism of action and compared the anthelmintic efficacy of cysteine proteinases from papaya, pineapple, fig, kiwi fruit and Egyptian milkweed in vitro using the rodent gastrointestinal nematode Heligmosomoides polygyrus.
Behnke, J.M., Buttle, D.J., Duce, I.R., Lowe, A.E., Stepek, G.   +4 more
core   +3 more sources

Effects of stem cell factor (kit-ligand) and interleukin-3 on the growth and serine proteinase expression of rat bone-marrow-derived or serosal mast cells [PDF]

, 1994
DM Haig, JF Huntley, A. Mackellar, GF Newlands, L. INGLIS, R Sangha, Donna Cohén, Andrew J. Hapel, SJ Galli, HR Miller   +9 more
openalex   +1 more source