Results 211 to 220 of about 409,825 (329)

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Positive Anti-Glomerular Basement Membrane and Proteinase 3-Antineutrophil Cytoplasmic Autoantibody in Infective Endocarditis-Associated Glomerulonephritis: A Diagnostic Challenge. [PDF]

Kidney Int Rep
Thanabalasingam SJ, Booth RA, Canney M, Milman N, Agostino A, Massicotte-Azarniouch D.   +5 more
europepmc   +1 more source

Correction to: Molecular mimicry among human proteinase 3 and bacterial antigens: implications for development of c-ANCA associated vasculitis. [PDF]

Oxf Open Immunol, 2022
europepmc   +1 more source

Anti-proteinase 3 antineutrophil cytoplasmic antibody reflects disease activity and predicts the response to steroid therapy in ulcerative colitis. [PDF]

BMC Gastroenterol, 2021
Aoyama Y, Inaba T, Takahashi S, Yasuhara H, Hiraoka S, Morimoto T, Colvin HS, Wato M, Ando M, Nakamura S, Mizobuchi K, Okada H.   +11 more
europepmc   +1 more source

Proteolysis of classic anti-neutrophil cytoplasmic autoantibodies (C-ANCA) by neutrophil proteinase 3 [PDF]

, 1995
Koert M. Dolman, Alessandro Jäger, Arnoud Sonnenberg, A E G KR VON DEM BORNEO, Roel Goldschmeding   +4 more
openalex   +1 more source

Proteinases and proteinase inhibitors in ejaculates of men with adnex affections [PDF]

, 1985
Brunner, H., Fink, Edwin, Friesen, A., Hofstetter, A., Jochum, Marianne, Krause, W., Rothauge, C. F., Schießler, Hans, Schill, W.-B., Weidner, W.   +9 more
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Proteinase 3 (PR3)-Positive Perinuclear Anti-neutrophil Cytoplasmic Antibodies (pANCA) Vasculitis With Concurrent Invasive Aspergillosis Infection. [PDF]

Cureus
Smith D, Herminie V, Priya S, Shehata MZA.   +3 more
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Expression and purification of human neutrophil proteinase 3 from insect cells and characterization of ligand binding. [PDF]

PLoS One
Khorsand F, Haug BE, Kursula I, Reuter N, Brenk R.   +4 more
europepmc   +1 more source