Results 241 to 250 of about 357,202 (334)

Imaging of Lipid Droplets in Living Cells and Mice with Metabolic Dysfunction‐Associated Steatotic Liver Disease via a Galactose‐Modified Supramolecular Near‐Infrared Fluorescent Glycoprobe

Advanced Functional Materials, EarlyView.
A galactose‐modified supramolecular near‐infrared (NIR) glycoprobe, TCF‐FBN@Gal‐BSA, enables targeted delivery to the liver through the asialoglycoprotein receptor (ASGPR) and facilitates liver‐targeting fluorescence visualization of lipid droplets (LDs) in metabolic dysfunction‐associated steatotic liver disease (MASLD) mice.
Han‐Min Wang, Lei Dong, Qiu‐Lian Hao, Lu‐Lu Sun, Xin‐Rong Li, Yu‐Wei Yuan, Ming‐Ye Tang, Jin Gong, Yi Zang, Jia Li, Tony D. James, Xiao‐Peng He, Hai‐Hao Han   +12 more
wiley   +1 more source

Meningitic Escherichia coli-Induced Interleukin-17A Facilitates Blood-Brain Barrier Disruption via Inhibiting Proteinase 3/Protease-Activated Receptor 2 Axis. [PDF]

Front Cell Neurosci, 2022
Xu B, Chen J, Fu J, Yang R, Yang B, Huo D, Tan C, Chen H, Wang X.   +8 more
europepmc   +1 more source

Kallikrein inhibitors [PDF]

, 1979
Fink, Edwin, Fritz, Hans, Truscheit, Ernst   +2 more
core   +1 more source

Activation of Human Oral Epithelial Cells by Neutrophil Proteinase 3 Through Protease-Activated Receptor-2 [PDF]

, 2002
Akiko Uehara, Shunji Sugawara, Koji Muramoto, Haruhiko Takada   +3 more
openalex   +1 more source

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source

Systematic Histological Scoring Reveals More Prominent Interstitial Inflammation in Myeloperoxidase-ANCA Compared to Proteinase 3-ANCA Glomerulonephritis. [PDF]

J Clin Med, 2021
Hakroush S, Kluge IA, Ströbel P, Korsten P, Tampe D, Tampe B.   +5 more
europepmc   +1 more source

ANCA antigens, proteinase 3 and myeloperoxidase, are not expreΔed in endothelial cells

, 2000
William F. Pendergraft, David A. Alcorta, Mårten Segelmark, Yang Jia, Robin Tuttle, J. Charles Jennette, Ronald J. Falk, Gloria A. Preston   +7 more
openalex   +2 more sources

Effects of carboxy-terminal modifications of proteinase 3 (PR3) on the recognition by PR3-ANCA [PDF]

, 2003
Stephen A. Capizzi, Margaret A. Viss, Amber M. Hummel, David N. Fass, Ulrich Specks   +4 more
openalex   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Antineutrophil cytoplasmic antibodies to proteinase 3 in Wegener's granulomatosis: Epitope analysis using synthetic peptides

, 2001
Ymke M. van der Geld, Arjan Simpelaar, Ruurd van der Zee, Jan Willem Cohen Tervaert, Coen A. Stegeman, Pieter C. Limburg, Cees G. M. Kallenberg   +6 more
openalex   +1 more source