Results 11 to 20 of about 3,477,167 (351)
Proteinase Inhibitors: A Promising Drug Class for Treating Leishmaniasis
Current Drug Targets, 2014 This review presents and discusses the current status and perspectives of leishmaniasis treatment, with a special focus on the use of proteinase inhibitors.
Silva, Franklin Souza +6 more
core +2 more sources
Action of plant proteinase inhibitors on enzymes of physiopathological importance
Anais da Academia Brasileira de Ciências, 2009 Obtained from leguminous seeds, various plant proteins inhibit animal proteinases, including human, and can be considered for the development of compounds with biological activity.
Maria Luiza V. Oliva, Misako U. Sampaio
doaj +2 more sources
Primary structure of potato Kunitz-type serine proteinase inhibitor [PDF]
, 2000 The serine proteinase inhibitor (PSPI-51) isolated from potato tubers (Solanum tuberosum L,) comprises two protein species with pi 5.2 and 6.3, denoted as PSPI-21-5.2 and PSPI-21-6.3, respectively.
Mentele, Reinhard +3 more
core +1 more source
Pest protection conferred by a Beta vulgaris serine proteinase inhibitor gene. [PDF]
PLoS ONE, 2013 Proteinase inhibitors provide a means of engineering plant resistance to insect pests. A Beta vulgaris serine proteinase inhibitor gene (BvSTI) was fused to the constitutive CaMV35S promoter for over-expression in Nicotiana benthamiana plants to study ...
Ann C Smigocki +3 more
doaj +1 more source
Фармацевтичний журнал, 2019 Peptic ulcer of the stomach and duodenum is a complex gastroenterological disease multifactorial in pathogenesis. One of the key components of non-specific inflammation in peptic ulcer disease is the activation of proteinases in the gastric mucosa and ...
N. N. Kononenko +2 more
doaj +1 more source
Results of protease inhibitor instructions in patients in acute burning disease
Сучасні медичні технології, 2022 The purpose of the study was to determine the clinical efficiency of proteinase inhibitor usage in patients with burns. Materials and Methods. The results of studies performed in 32 patients with superficial and deep burns were analyzed: 12 patients of ...
O.M. Lynnyk, H.P. Kozynets, O.I. Osadcha
doaj +1 more source
A Proteinase and Proteinase Inhibitor of Mammalian Sperm Acrosomes [PDF]
Biology of Reproduction, 1973 Acrosomal extracts of epididymal boar and epididymal and ejaculated rooster spermatozoa possess high proteinase (acrosin) activity. Less activity is present in extracts from ejaculated human, monkey, and ram sperm or epididymal rabbit, stallion, and ram sperm, and virtually none can be found in extracts at neutral pH of ejaculated sperm of the rabbit ...
L J, Zaneveld +2 more
openaire +2 more sources
Cysteine peptidases and their inhibitors in breast and genital cancer.
Folia Histochemica et Cytobiologica, 2010 Cysteine proteinases and their inhibitors probably play the main role in carcinogenesis and metastasis. The metastasis process need external proteolytic activities that pass several barriers which are membranous structures of the connective tissue which ...
Magdalena Milan +7 more
doaj +1 more source
The effects of a plant proteinase inhibitor from Enterolobium contortisiliquum on human tumor cell lines [PDF]
, 2011 Supplementary to the efficient inhibition of trypsin, chymotrypsin, plasma kallikrein, and plasmin already described by the EcTI inhibitor from Enterolobium contortisiliquum, it also blocks human neutrophil elastase (K(iapp)=4.3 nM) and prevents phorbol ...
Sampaio, Misako U. [UNIFESP] +21 more
core +1 more source
EFFECT OF SILVER NANOPARTICLES IN EXPERIMENTAL PERITONITIS
Бюллетень сибирской медицины, 2015 In our research we have investigated the effect of intraperitoneal introduction of silver nanoparticles solution (linear particle size of 10–20 nm) into intact animals and in the simulation of experimental peritonitis.
D. V. Chegodar +2 more
doaj +1 more source