Results 21 to 30 of about 734,343 (302)

Role of Certain Elicitors on the Chemical Induction of Resistance in Tomato against the Leaf Caterpillar Spodoptera litura Fab.

Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 2008
Mill. The four presumptive defenses manipulated were protinase inhibitors, polyphenol oxidase, peroxidase and lipoxygenase. The elicitors used were jasmonic acid (JA), salicylic acid (SA) and PGPR Pseudomonas aeruginosa.
M. MELVIN JOE, N. MUTHUKUMARAN
doaj   +1 more source

Biochemical markers assessing rate of reparative processes in patients with infiltrative pulmonary tuberculosis

Инфекция и иммунитет, 2023
Theeffectiveness of chemotherapy for infiltrative pulmonary tuberculosis (ITL) is determined by proper timing and adequacy of treatment. The speed of reparative changes in the pulmonary parenchyma is associated with the effectiveness of therapy ...
Dilyara S. Esmedlyaeva, Nina P. Alekseeva, Marina E. Dyakova   +2 more
doaj   +1 more source

Inibidores de proteases de hospedeiros nativos e exóticos e sua ação em intestinos de lagartas de Thyrinteina leucoceraea Proteinase inhibitors of novel and native host plants and their action in midgut of Thyrinteina leucoceraea caterpillars

Revista Árvore, 2008
Os insetos podem causar perdas consideráveis aos seus hospedeiros, entretanto alguns deles habitam em plantas sem causar-lhes danos. Por exemplo, Thyrinteina leucoceraea, herbívoro da entomofauna brasileira, pode ser encontrado na goiabeira, hospedeiro ...
Jeanne Scardini Marinho, Maria Goreti Almeida Oliveira, Raul Narciso Carvalho Guedes, Angelo Pallini, Claudinei Lima Oliveira   +4 more
doaj   +1 more source

Melia azedarach L. extract induced the production of phytocystatin in passion fruit leaves

Hoehnea, 2021
Phytocystatins belong to the family of cysteine proteinases inhibitors. These proteinase inhibitors have crucial functions in plant defense against insects and pathogens attack. In the present study Melia azedarach L. extract acts as an elicitor of plant
Alyne Bispo Rodrigues, César Luis Siqueira Junior   +1 more
doaj   +1 more source

Lipopeptides as dimerization inhibitors of HIV-1 protease [PDF]

, 1999
In AIDS therapy, attempts have been made to inhibit the virus-encoded enzymes, e.g, HIV-1 protease, using active site-directed inhibitors. This approach is questionable, however, due to virus mutations and the high toxicity of the drugs, An alternative ...
Schramm, W., Schramm, H. J., Büttner, J., de Rosny, E., Dick, A., Reboud-Ravaux, M.   +5 more
core   +1 more source

Potential therapeutic target identification in the novel 2019 coronavirus: insight from homology modeling and blind docking study

Egyptian Journal of Medical Human Genetics, 2020
Background The 2019-nCoV which is regarded as a novel coronavirus is a positive-sense single-stranded RNA virus. It is infectious to humans and is the cause of the ongoing coronavirus outbreak which has elicited an emergency in public health and a call ...
Olanrewaju Ayodeji Durojaye, Talifhani Mushiana, Henrietta Onyinye Uzoeto, Samuel Cosmas, Victor Malachy Udowo, Abayomi Gaius Osotuyi, Glory Omini Ibiang, Miapeh Kous Gonlepa   +7 more
doaj   +1 more source

Investigating Polypharmacology Through Targeting Known Human Neutrophil Elastase Inhibitors to Proteinase 3 [PDF]

, 2023
Using a combination of state-of-the-art free energy computational approaches together with in vitro IC50 assays, we evaluated the polypharmacological potential of a scaffold currently in clinical trials for inhibition of human neutrophil elastase (HNE ...
Fahimeh, Khorsand, Luis F, Cervantes, Ruth, Brenk, Juha Ilmari, Vahokovski, Nathalie, Reuter, Parveen, Gartan, Charles L., Brooks, Pushpak, Mizar, Bengt Erik, Haug   +8 more
core   +2 more sources

Antiviral proteinase inhibitors of plant and animal origin

Iberoamerican Journal of Medicine, 2020
Introduction: Over the past 10 years, much attention has been paid to the development of new antiviral drugs based on the suppression of the proteolytic activity of enzymes by trypsin inhibitors of plant and animal origin.
Valentina Divocha, Irina Komarevzeva
doaj   +1 more source

A KLK4 proteinase substrate capture approach to antagonize PAR1

Scientific Reports, 2021
Proteinase-activated receptor-1 (PAR1), triggered by thrombin and other serine proteinases such as tissue kallikrein-4 (KLK4), is a key driver of inflammation, tumor invasiveness and tumor metastasis.
Eitan Rabinovitch, Koishiro Mihara, Amiram Sananes, Marianna Zaretsky, Michael Heyne, Julia Shifman, Amir Aharoni, Morley D. Hollenberg, Niv Papo   +8 more
doaj   +1 more source

Inhibition of Plant-Pathogenic Fungi by the Barley Cystatin Hv-CPI (Gene Icy) Is Not Associated with Its Cysteine-Proteinase Inhibitory Properties

Molecular Plant-Microbe Interactions, 2003
The recombinant barley cystatin Hv-CPI inhibited the growth of three phytopathogenic fungi (Botrytis cinerea, Colletotrichum graminicola, and Plectosphaerella cucumerina) and the saprotrophic fungus Trichoderma viride.
M. Martínez, E. López-Solanilla, P. Rodríguez-Palenzuela, P. Carbonero, I. Díaz   +4 more
doaj   +1 more source