Results 191 to 200 of about 28,680 (262)

Proteinases

, 1993
Jochum, Marianne, Machleidt, W., Neuhof, H., Fritz, Hans   +3 more
openaire   +2 more sources

Compensatory Mitophagy via NEDD4/HIF‐1α/BNIP3 Pathway Restrains EndMT and Renal Allograft Interstitial Fibrosis Induced by TNFα

Advanced Science, EarlyView.
The role of TNFα in the process of renal allograft interstitial fibrosis is complex and multifaceted. As it can promote renal allograft interstitial fibrosis by inducing mitochondrial dysfunction and EndMT, and also mediating compensatory mitophagy through the NEDD4–HIF‐1α–BNIP3 pathway, which clears damaged mitochondria and inhibits EndMT, thereby ...
Dengyuan Feng, Qinghuan Shen, Junqi Zhang, Jiawen Liu, Zeping Gui, Zijie Wang, Qianguang Han, Shuang Fei, Hao Chen, Li Sun, Jun Tao, Zhijian Han, Xiaobing Ju, Min Gu, Jianjian Zhang, Ruoyun Tan   +15 more
wiley   +1 more source

PhyCysID: Plant Cystatin Protein Prediction by an Artificial Intelligence Approach. [PDF]

J Chem Inf Model
Aqil S, Cadavid IC, Rodrigues NF, Balbinott N, Zanatta G, Margis R.   +5 more
europepmc   +1 more source

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

Advanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang, Jianhua Li, Huilu Zhang, Qi Qin, Yichen Huang, Xiaofan Tian, Chao Sun, Binbin Li, Zhengxin Wang, Xin Zhang   +9 more
wiley   +1 more source

The Multifaceted Roles of Neutrophil Death in COPD and Lung Cancer. [PDF]

J Respir Biol Transl Med
Wan A, Chen D.
europepmc   +1 more source

Unveiling the Roles of Cysteine Proteinases F and W: From Structure to Pathological Implications and Therapeutic Targets. [PDF]

Cells
Zdravkova K, Mijanovic O, Brankovic A, Ilicheva PM, Jakovleva A, Karanovic J, Pualic M, Pualic D, Rubel AA, Savvateeva LV, Parodi A, Zamyatnin AA.   +11 more
europepmc   +1 more source

Effect of <i>Metarhizium anisopliae</i> IPPM202 Extracellular Proteinases on Midgut of <i>Locusta migratoria manilensis</i>. [PDF]

Insects
Huang L, Wang Z, Davaasambuu U, Li H, McNeill MR, Cao G, Tu X, Liu C, Zhang Z, Wang G, Chang J.   +10 more
europepmc   +1 more source

Neutrophils in idiopathic pulmonary fibrosis patients are phenotypically distinct from controls. [PDF]

ERJ Open Res
Chong DLW, Sahota J, Denneny EK, Mikolasch TA, Garthwaite HS, Heightman M, Booth H, Porter JC.   +7 more
europepmc   +1 more source

MMP2 sheds Glypican-4 to suppress Slit3-Robo4 signaling and angiogenesis. [PDF]

Proteoglycan Res
Xiao W, Orta AR, Yue J, Song X, Yin H, Wang L.   +5 more
europepmc   +1 more source

Matrix Metalloproteinase Inhibition in Melanoma. [PDF]

Exp Dermatol
Zhang E, Thakur V, Bedogni B.
europepmc   +1 more source