Results 141 to 150 of about 104,802 (338)

Cleavage of Fibrinogen by Proteinases Elicits Allergic Responses Through Toll-Like Receptor 4

Science, 2013
Valentine Millien, Wen Lu, J. Shaw, Xiaoyi Yuan, Garbo Mak, Luz Roberts, Lizhen Song, J. Knight, C. Creighton, A. Luong, F. Kheradmand, D. Corry   +11 more
semanticscholar   +1 more source

Proteinase-activated receptor 1 (PAR₁)-mediated cellular effects of coagulation factor XI in vascular smooth muscle cells

, 2019
Katsuya Hirano, Wenhua Liu, Takeshi Hiashimoto, Tetsuo Yamashita   +3 more
openalex   +2 more sources

Antimalarial effects of vinyl sulfone cysteine proteinase inhibitors [PDF]

, 1996
Philip J. Rosenthal, Jed Olson, G K Lee, James T. Palmer, Jeffrey L. Klaus, David Rasnick   +5 more
openalex   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Inhibition of bone resorption in culture by inhibitors of thiol proteinases [PDF]

, 1980
Jean‐Marie Delaissé, Yves Eeckhout, Gilbert Vaes   +2 more
openalex   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Contractile actions of proteinase‐activated receptor‐derived polypeptides in guinea‐pig gastric and lung parenchymal strips: evidence for distinct receptor systems [PDF]

, 2001
Mahmoud Saifeddine, Bahjat Al‐Ani, Sumiti Sandhu, Suranga J. Wijesuriya, Morley D. Hollenberg   +4 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Tissue injury in inflammation. Oxidants, proteinases, and cationic proteins.

Journal of Clinical Investigation, 1987
P M Henson, R B Johnston
semanticscholar   +1 more source

INHIBITION OF THE PROTEINASE AND ESTERASE ACTIVITIES OF TRYPSIN AND CHYMOTRYPSIN BY DIISOPROPYL FLUOROPHOSPHATE: CRYSTALLIZATION OF INHIBITED CHYMOTRYPSIN

, 1949
Eugene F. Jansen, M.-D. Fellows Nutting, Rosie Jang, A.K. Balls   +3 more
openalex   +1 more source