Results 161 to 170 of about 40,422 (295)

A Functional Shift of IGFBP3 in Osteoarthritis: From Cartilage Protection to Disease Promotion. [PDF]

J Inflamm Res
Chen J, Liu X, Gu Y, Zhang H, Yang Y, Li Z.   +5 more
europepmc   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

Enhancing Nutritional and Health Benefits of Wheat Bran Through Bifunctional LAB Screening and BCAA-Enriched Fermentation. [PDF]

Foods
Lee BH, Han SO, Hong JS, Jeong SJ, Hong JY, Kim YJ.   +5 more
europepmc   +1 more source

Conformational Switching of Proteins on Material Surfaces Enabled by Peptide‐Oriented Adsorption

Advanced Functional Materials, EarlyView.
Responsive biointerfaces could be achieved using conformationally responsive proteins; however, their interconversion can be lost upon surface adsorption. Herein, we demonstrate that the incorporation a Au binding peptide into calmodulin allows for binding control on Au wherein the protein retains conformational switching. This capability was confirmed
Sakthirupini Ramamurthy, Kyle B. Meerbott, Lorenzo Travaglini, Garima S. Dobhal, Artur Sawicki, Marc R. Knecht, Tiffany R. Walsh, Dominic J. Glover   +7 more
wiley   +1 more source

SARS-CoV-2 disrupts the integrity of a human blood-brain barrier model in the absence of infection. [PDF]

J Neurovirol
Jmii H, Haverty R, Rochfort KD, Fletcher NF.   +3 more
europepmc   +1 more source

Concentration‐Dependent Self‐Assembly and Nanoparticle Maturation of Reflectins

Advanced Functional Materials, EarlyView.
Within squid skin, structural coloration arises from iridophores whose Bragg reflector‐like ultrastructures contain high‐refractive‐index reflectin proteins. Coarse‐grained molecular dynamics simulations and dynamic light scattering measurements reveal how concentration modulates reflectin A2 self‐assembly.
Andrew H. Cannon, Albert L. Kwansa, Nikhil Kaimal, Arsenii Panteleev, Ashlynn Zhang, Loc Nguyen, Preeta Pratakshya, Alon A. Gorodetsky, Yaroslava G. Yingling   +8 more
wiley   +1 more source

From Oral Candidiasis to Candidemia: A Review of Superficial to Invasive Progression. [PDF]

Microbiologyopen
Jerez JR, Ambrosio MV, Fernandes MEO, Mima EGO.   +3 more
europepmc   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Effect of the BD132 Dendron Against <i>Candida tropicalis</i>: Inhibition of Biofilm Formation and Enzymatic and Structural Alterations. [PDF]

Pharmaceutics
García-Porcel E, Gómez-Casanova N, Pérez-Serrano J, Copa-Patiño JL, Heredero-Bermejo I.   +4 more
europepmc   +1 more source

Genetically Programmed Shape‐Morphing of Engineered Living Materials

Advanced Functional Materials, EarlyView.
Here, bacterial and mammalian engineered living materials (ELMs) are presented, in which living cells direct genetically programmed and enzymatically mediated shape‐morphing. The resulting deformation and shape‐recovery can be actuated in a genetically controlled manner by an ELM incorporating out‐of‐equilibrium counteracting biochemical reactions with
Jan Becker, Yuchen Liu, Miguel Baños, Rosanne Schmachtenberg, Mahmudul Hasan, Claudia Fink‐Straube, Luai R. Khoury, Wilfried Weber   +7 more
wiley   +1 more source