Results 31 to 40 of about 40,422 (295)

Plasmodium falciparum proteinases: cloning of the putative gene coding for the merozoite proteinase for erythrocyte invasion (MPEI) and determination of hydrolysis sites of spectrin by Pf37 proteinase

open access: yesMemorias do Instituto Oswaldo Cruz, 1994
Numerous proteinase activities have been shown to be essential for the survival of Plasmodium falciparum. One approach to antimalarial chemotherapy, would be to block specifically one or several of these activities, by using compounds structurally ...
I. Florent   +9 more
doaj   +1 more source

Purification and some Properties of Proteinases from Calf Thymus [PDF]

open access: yes, 1972
Calf thymus was used for the investigation of intracellular proteinases. The tissue was homogenized, centrifuged at a low speed and applied on DEAE-cellulose.
Lebez, D.   +3 more
core   +1 more source

Pathogenetic role of proteinase-inhibitor system in the development of local and systemic pathology

open access: yesPatologìâ, 2012
The experimental and clinical research of nonspecific proteinase-inhibitor system components role in pathogenesis of inflammation and ischemia-reperfusion syndrome on the level of organism and on organ level was conducted. Common mechanisms of changes
I. I. Fomochkin, A. V Kubyshkin
doaj   +1 more source

Carboxy terminal extended phytocystatins are bifunctional inhibitors of papain and legumain cysteine proteinases

open access: yes, 2007
Plant legumains are cysteine proteinases putatively involved in processing endogenous proteins. Phytocystatins (PhyCys) have been described as plant inhibitors of papain-like cysteine proteinases.
Mercedes Diaz-Mendoza   +7 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Investigação sobre a adaptação do inseto praga de cereais Tenebrio molitor a inibidores de proteinases digestivas [PDF]

open access: yes, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Bioquímica, Florianópolis, 2010Nas larvas de Tenebrio molitor (verme do trigo) são encontrados variados tipos de proteinases ...
Alexandre, Daniel
core  

Aspartic proteinases in Antarctic fish

open access: yes, 2009
The present review surveys several recent studies of the aspartic proteinases from Antarctic Notothenioidei, a dominating fish group that has developed a number of adjustments at the molecular level to maintain metabolic function at low temperatures ...
Maria G   +10 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Anti-Candida Activity of Geraniol: Effect on Hydrolytic Enzyme Secretion and Biofilm Formation

open access: yesJournal of Pure and Applied Microbiology, 2018
Existing antifungal drugs available today are low in efficacy, high in toxicity and cause multidrug resistance. Anti-Candida potential of geraniol, an acyclic monoterpene alcohol was evaluated and secretion of hydrolytic enzymes, adherence and biofilm ...
Yamini Sharma   +4 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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