Results 181 to 190 of about 10,718,710 (345)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

In vitro synthesis of active recombinant orthoflavivirus nonstructural polyproteins in detergent micelles for biochemical analysis. [PDF]

Npj Viruses
Takahashi H, Uchiage Y, Emura Y, Yamagami R, Abe M, Yoshii K, Tajima S, Lim CK, Hori H, Vasudevan SG, Sawasaki T.   +10 more
europepmc   +1 more source

Characterization of the Promoter Region of the Mouse Gene Encoding the Steroidogenic Acute Regulatory Protein [PDF]

, 1997
Kathleen M. Caron, Yayoi Ikeda, Shiu-Ching Soo, Douglas M. Stocco, Keith L. Parker, Barbara J. Clark   +5 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

(Re)defining the human chromatome: an integrated meta-analysis of localization, function, abundance, physical properties, and domain composition of chromatin proteins. [PDF]

Nucleic Acids Res
Gribkova AK, Armeev GA, Kirpichnikov MP, Shaytan AK.   +3 more
europepmc   +1 more source

Direct prediction of intrinsically disordered protein conformational properties from sequence [PDF]

Jeffrey M. Lotthammer, Garrett M. Ginell, Daniel Griffith, Ryan J. Emenecker, Alex S. Holehouse   +4 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Characterization and Comparison of Milk Fat Globule Membrane Proteins, Whey Protein Concentrate, and Micellar Casein Concentrate. [PDF]

Food Sci Nutr
Wang J, Ji X, Bian Z, Liu Y, Chen W, Fan C, Li J.   +6 more
europepmc   +1 more source

Phosphorylation of connexin 32, a hepatocyte gap‐junction protein, by cAMP‐dependent protein kinase, protein kinase C and Ca²⁺/calmodulin‐dependent protein kinase II [PDF]

, 1990
Juan C. Sáez, Angus C. Nairn, Andrew J. Czernik, David C. Spray, Elliot L. Hertzberg, Paul Greengard, Michael V. L. Bennett   +6 more
openalex   +1 more source

Bacillus thuringiensis and Its Pesticidal Crystal Proteins

Microbiology and Molecular Biology Reviews, 1998
E. Schnepf, N. Crickmore, J. Rie, D. Lereclus, J. Baum, J. Feitelson, D. R. Zeigler, D. Dean   +7 more
semanticscholar   +1 more source