Proteomic landscape of multidimensional aging phenotypes. [PDF]
Cao Z, Chen H, Min J, Xu C.
europepmc +1 more source
LIPIDE AND PROTEIN COMPOSITION OF FOUR FRACTIONS ACCOUNTING FOR TOTAL SERUM LIPOPROTEINS
Lewis A. Hillyard +3 more
openalex +1 more source
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source
Plasma circulating extracellular vesicles reveal dysregulation of synaptic signaling in SHIV-infected rhesus macaque. [PDF]
Chandra PK +7 more
europepmc +1 more source
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source
Identifying the quantity profiles of amyloid signature proteins in different types of renal amyloidosis. [PDF]
Wang S, Li D, Zhang X, Zhou F, Wang S.
europepmc +1 more source
STUDIES ON THE NATURE OF THE COMBINATION BETWEEN CERTAIN ACID DYES AND PROTEINS
L. Chapman +2 more
openalex +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source
Integrating multi-modal omics to identify therapeutic atherosclerosis pathways for coronary heart disease. [PDF]
de Ruiter SC +9 more
europepmc +1 more source

