Results 201 to 210 of about 10,718,710 (345)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Short-Time Germination Modifies Chickpea Grains and Enhances the Production of High-Quality Functional Beverages: Insights into the Soaking Stage in Transformation Processes

ACS Omega
Juliana Alves Diniz, Sara Aparecida Mendes Diniz Antonio, Ana Carolina Batista da Silva Lemos, Lara Campos Borim, Matheus Monaco, Sinézio Inácio da Silva Júnior, Olga Luisa Tavano   +6 more
doaj   +1 more source

Impacts of heat and noncovalent bonding on interfacial property and structure of goat milk fat globule membrane proteins. [PDF]

NPJ Sci Food
Luo Y, Song Y, Su L, Zhou Y, Chen C, Du Z, Sun Y.   +6 more
europepmc   +1 more source

Insight into the Effects of Hydrodynamic Cavitation at Different Ionic Strengths on Physicochemical and Gel Properties of Myofibrillar Protein from Tilapia (Oreochromis niloticus) [PDF]

Kun Xie, Feng Yang, Xian’e Ren, Yongchun Huang, Fengyan Wei   +4 more
openalex   +1 more source

Oxidative Modification of Nuclear Mitogen-activated Protein Kinase Phosphatase 1 Is Involved in Transforming Growth Factor β1-induced Expression of Plasminogen Activator Inhibitor 1 in Fibroblasts [PDF]

, 2010
Rui-Ming Liu, Jinah Choi, Jian-He Wu, Kimberly A. Gaston Pravia, Karen Lewis, Jeffrey D. Brand, Nabora Soledad Reyes de Mochel, David M. Krzywanski, J. David Lambeth, James S. Hagood, Henry Jay Forman, Victor J. Thannickal, Edward M. Postlethwait   +12 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Proteomics and Bioinformatics Profiles of Human Mesothelial Cell Line MeT-5A. [PDF]

Proteomes
Watkin RL, Kazanjian AA, Damicis JR, Yohannes E.   +3 more
europepmc   +1 more source

In-situ biophysical characterization of high-concentration protein formulations using w NMR [PDF]

Jing Song, Marc B. Taraban, Y. Bruce Yu, Lynn Lu, Pallavi Guha Biswas, Wei Xu, Hanmi Xi, Akhilesh Bhambhani, Guangli Hu, Yongchao Su   +9 more
openalex   +1 more source

C-Reactive Protein Predicts Hematoma Growth in Intracerebral Hemorrhage [PDF]

, 2013
Mario Di Napoli, Adrian Parry‐Jones, Craig J. Smith, Stephen J. Hopkins, Mark Slevin, Luca Masotti, Verónica Campi, Puneetpal Singh, Francesca Papa, Aurel Popa‐Wagner, Valerica Tudorică, Daniel Agustín Godoy   +11 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source