Results 201 to 210 of about 13,117,352 (339)

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

TDP-43 pathology is associated with divergent protein profiles in ALS brain and spinal cord. [PDF]

Acta Neuropathol Commun
Feneberg E, Thompson AG, Charles PD, Vendrell I, Kessler BM, Fischer R, Ansorge O, Gray E, Talbot K, Turner MR.   +9 more
europepmc   +1 more source

Proteins from hyperthermophilic Archeae [PDF]

, 1992
Hensel, R., Jakob, I., Lottspeich, Fritz, Scheer, Hugo   +3 more
core  

THE INFLUENCE OF PROTEIN INTAKE ON THE UREA CLEARANCE IN NORMAL MAN [PDF]

, 1934
William Goldring, Louis Razinsky, Marc S. Greenblatt, Sidney Cohen   +3 more
openalex   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Fractionation of basic proteins and polypeptides. Clupeine and salmine [PDF]

, 1956
F. S. Scanes, B. T. Tozer
openalex   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Application of the Mass Spectrometry-High-Throughput Technique Over the Immunohistochemical Analysis for Human Brain Tumor Diagnosis and Prognosis: Insights Into Biomarkers' Identification for the Case Study of Grade IV Astrocytomas and Meningiomas. [PDF]

Biomed Chromatogr
Louati K, Kolsi F, Mellouli M, Louati H, Kallel R, Zribi R, Borni M, Hakim LS, Maalej A, Choura S, Chamkha M, Sayadi S, Khemakhem Z, Boudawara TS, Boudawara MZ, Zribi K, Safta F.   +16 more
europepmc   +1 more source

Cell cycle proteins as promising targets in cancer therapy

Nature Reviews. Cancer, 2017
T. Otto, P. Sicinski
semanticscholar   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source