Results 31 to 40 of about 126,260 (296)
Chylous Urine with Massive Proteinuria – Not Every Proteinuria Requires Renal Biopsy!
Indian Journal of Kidney Diseases, 2023 Chyluria is a condition characterized by abnormal leakage of lymphatic fluid into the urinary system. It is most commonly caused by filarial parasites in the endemic Indian population.
Siddharth Herur +4 more
doaj +1 more source
Arthritis Care &Research, Accepted Article.Objective We evaluated the role of 25‐hydroxy vitamin D, prednisone and other risk factors for bone mineral density (BMD) loss and osteoporosis in systemic lupus erythematosus (SLE). Methods We calculated the association between 25‐hydroxy vitamin D [25(OH)D] levels and other potential risk factors with BMD measures (spine T‐scores) and osteoporosis ...
Nima Madanchi +4 more
wiley +1 more source
Scientific ReportsRegorafenib is the first multikinase inhibitor for treating metastatic colorectal cancer (mCRC). Proteinuria is a frequently encountered adverse effect, regardless of prior administration of vascular endothelial growth factor inhibitors. Herein, we aimed
Yoshitaka Saito +3 more
doaj +1 more source
PLoS ONE, 2011 BackgroundIsolated gestational proteinuria may be part of the pre-eclampsia disease spectrum. Confirmation of its association with established pre-eclampsia risk factors and higher blood pressure in uncomplicated pregnancies would support this concept ...
Corrie Macdonald-Wallis +5 more
doaj +1 more source
Proteinuria Thresholds Are Irrational: A Call for Proteinuria Indexing [PDF]
Nephron Clinical Practice, 2010 Current guidelines for chronic kidney disease (CKD) diagnosis, referral and management are based on absolute thresholds of proteinuria/albuminuria with no reference to the residual nephron mass or function. This is illogical since the severity of proteinuria is a direct reflection of the number of filtering nephrons as well as their pathology and the ...
Timothy J, Ellam, Meguid, El Nahas
openaire +2 more sources
Electrochemical Biosensor for Rapid Detection of Acute Rejection in Kidney Transplants
Advanced Healthcare Materials, EarlyView.A low‐cost, rapid electrochemical immunosensor coated with a novel antifouling nanocomposite enables single‐step, dual‐biomarker profiling directly from unprocessed urine. Application in a clinical study shows accurate discrimination of acute rejection in kidney transplants from other acute kidney injuries via machine learning.
Rohit Gupta +9 more
wiley +1 more source
Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS
Advanced Science, EarlyView.This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu +14 more
wiley +1 more source
Association between proteinuria and placental pathology in preeclampsia: A retrospective study
SAGE Open Medicine, 2021 Introduction: Preeclampsia develops due to placental insufficiency and systemic proinflammatory and antiangiogenic mediator release, with ensuing systemic endothelial dysfunction.
Dominique Suzanne Genest +3 more
doaj +1 more source
Growth hormone induces mitotic catastrophe of glomerular podocytes and contributes to proteinuria [PDF]
, 2021 Rajkishor Nishad +6 more
openalex +1 more source
Advanced Science, EarlyView.TREM2 recognizes NETs‐derived MPO to promote DC maturation and antigen presentation, thereby exacerbating the autoimmune response in SLE. Mechanistically, TREM2 activation triggers the DAP12/SYK/ERK cascade and enhances NETs internalization by DCs, which in turn activates the cGAS/STING signaling pathway.
Jingxian Shu +7 more
wiley +1 more source