Results 31 to 40 of about 187,783 (355)

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

Hepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou, Yongkun Sun, Wen Zhang, Jiajia Yuan, Zhi Peng, Wei Wang, Jifang Gong, Lin Yang, Yanshuo Cao, Hong Zhao, Chao Chen, Weifeng Wang, Lin Shen, Aiping Zhou   +13 more
wiley   +1 more source

Nonalbumin Proteinuria in Islet Transplant Recipients

Cell Transplantation, 2010
The aim of this study was to evaluate the importance of nonalbumin-predominant proteinuria on kidney function (KF) after islet transplantation (ITx). Twenty-four-hour proteinuria and albuminuria were available in 27 recipients.
Cristiane B. Leitão, Tatiana Froud, Pablo Cure, Thipaporn Tharavanij, Antonello Pileggi, Camillo Ricordi, Rodolfo Alejandro   +6 more
doaj   +1 more source

The prevalence of immunologic injury in renal allograft recipients with de novo proteinuria. [PDF]

PLoS ONE, 2012
Post-transplant proteinuria is a common complication after renal transplantation; it is associated with reduced graft and recipient survival. However, the prevalence of histological causes has been reported with considerable variation.
Qiquan Sun, Song Jiang, Xue Li, Xianghua Huang, Kenan Xie, Dongrui Cheng, Jinsong Chen, Shuming Ji, Jiqiu Wen, Mingchao Zhang, Caihong Zeng, Zhihong Liu   +11 more
doaj   +1 more source

Diagnostic and prognostic performance of urinary neutrophil gelatinase‐associated lipocalin in patients with cirrhosis and acute kidney injury

Hepatology, EarlyView., 2022
Diagnostic and prognostic ability of urinary NGAL in patients with cirrhosis and AKI. Abstract Background and Aims Acute kidney injury (AKI) commonly occurs in patients with decompensated cirrhosis. Urinary neutrophil gelatinase–associated lipocalin (uNGAL) could help discriminate between different etiologies of AKI.
Carmine Gambino, Salvatore Piano, Matteo Stenico, Marta Tonon, Alessandra Brocca, Valeria Calvino, Simone Incicco, Nicola Zeni, Roberta Gagliardi, Chiara Cosma, Martina Zaninotto, Patrizia Burra, Umberto Cillo, Daniela Basso, Paolo Angeli   +14 more
wiley   +1 more source

Preoperative proteinuria is associated with long-term progression to chronic dialysis and mortality after coronary artery bypass grafting surgery. [PDF]

PLoS ONE, 2012
AIMS: Preoperative proteinuria is associated with post-operative acute kidney injury (AKI), but whether it is also associated with increased long-term mortality and end-stage renal disease (ESRD) is unknown.
Vin-Cent Wu, Tao-Min Huang, Pei-Chen Wu, Wei-Jie Wang, Chia-Ter Chao, Shao-Yu Yang, Chih-Chung Shiao, Fu-Chang Hu, Chun-Fu Lai, Yu-Feng Lin, Yin-Yi Han, Yih-Sharng Chen, Ron-Bin Hsu, Guang-Huar Young, Shoei-Shen Wang, Pi-Ru Tsai, Yung-Ming Chen, Ting-Ting Chao, Wen-Je Ko, Kwan-Dun Wu, NSARF Group   +20 more
doaj   +1 more source

Association of the clinicopathological characteristics and proteinuria remission of pediatric IgAV with nephrotic-range proteinuria: A retrospective cohort study

Frontiers in Pediatrics, 2022
BackgroundIgA vasculitis (IgAV) combined with nephrotic-range proteinuria is uncommon, and nephrotic-range proteinuria is considered a risk factor for poor prognosis in children with IgAV. There are few clinical studies with large samples.MethodsChildren
Zhijuan Kang, Zhijuan Kang, Mai Xun, Zhihui Li, Zuocheng Yang   +4 more
doaj   +1 more source

Drug-like analogues of the parasitic worm-derived immunomodulator ES-62 are therapeutic in the MRL/Lpr model of systemic lupus erythematosus [PDF]

, 2015
Introduction ES-62, a phosphorylcholine (PC)-containing immunomodulator secreted by the parasitic worm Acanthocheilonema viteae, protects against nephritis in the MRL/Lpr mouse model of systemic lupus erythematosus (SLE).
Harnett, M. M., Harnett, W., Pineda, M. A., Rodgers, D. T., Suckling, C. J.   +4 more
core   +1 more source

Mechanisms of Proteinuria in HIV [PDF]

Frontiers in Medicine, 2021
Proteinuria is common in the setting of HIV infection, and may reflect comorbid kidney disease, treatment-related nephrotoxicity, and HIV-related glomerular diseases. The mechanisms of podocyte and tubulointerstial injury in HIV-associated nephropathy (HIVAN) have been the subject of intense investigation over the past four decades.
Gentzon Hall, Gentzon Hall, Christina M. Wyatt, Christina M. Wyatt   +3 more
openaire   +4 more sources

Functional characterization of a novel TP53RK mutation identified in a family with Galloway–Mowat syndrome

Human Mutation, Volume 43, Issue 12, Page 1866-1871, December 2022., 2022
Abstract Galloway–Mowat syndrome (GAMOS) is a very rare condition characterized by early‐onset nephrotic syndrome and microcephaly with variable neurologic features. While considerable genetic heterogeneity of GAMOS has been identified, the majority of cases are caused by pathogenic variants in genes encoding the four components of the Kinase ...
Ernestine Treimer, Tugba Kalayci, Sven Schumann, Ilknur Suer, Sara Greco, Denny Schanze, Michael J. Schmeisser, Susanne J. Kühl, Martin Zenker   +8 more
wiley   +1 more source

Circulating antigen tests and urine reagent strips for diagnosis of active schistosomiasis in endemic areas [PDF]

, 2015
Background: Point-of-care (POC) tests for diagnosing schistosomiasis include tests based on circulating antigen detection and urine reagent strip tests.
Bossuyt, P.M.M., Gopalakrishna, G., Lamberton, P., Leeflang, M.M.G., Ochodo, E.A., Polman, K., Reitsma, J.B., Spek, B., van Lieshout, L.   +8 more
core   +3 more sources