Roles of Gut Microbiota and Associated Metabolites in Clostridioides difficile Infection
Clostridioides difficile infection (CDI), is the most common healthcare problem primarily involving the colon of individuals who’s gut microbiota has been disrupted.
GAO YAN +6 more
doaj +1 more source
The planthopper Pentastiridius leporinus (Hempiptera: Cixiidae) is the main vector of two bacterial pathogens: the γ-proteobacterium ‘Candidatus Arsenophonus phytopathogenicus’ and the stolbur phytoplasma ‘Candidatus Phytoplasma solani’.
André Rinklef +7 more
doaj +1 more source
Early matrine intervention of gut microbiota for type 2 diabetes prevention
How matrine influences gut microbiota imbalance to prevent the progression of diabetes remains unclear. We conduct experiments using mice to simulate the stages of diabetes development and matrine intervention. Combined with amplicon sequencing, we find that the gut microbiota of diabetic mice continuously changes with the progression of the disease ...
Zhexue Sun +4 more
wiley +1 more source
Neokomagataeagen. nov., with Descriptions ofNeokomagataea thailandicasp. nov. andNeokomagataea tanensissp. nov., Osmotolerant Acetic Acid Bacteria of the α-Proteobacteria [PDF]
Pattaraporn Yukphan +7 more
openalex +1 more source
Ribosomal RNA operon copy number: A trait‐informed framework to close the microbial cultivation gap
The vast majority of microbes remain uncultured, constraining functional validation and limiting microbiome‐based applications. We show that ribosomal RNA operon (rrn) copy number—a stable, phylogenetically conserved genomic trait—is strongly correlated with cultivation outcomes across ecosystems.
Yuxiao Huang +8 more
wiley +1 more source
Evidence for liver metabolism of gut‐derived microbial compounds into beneficial secondary metabolites has been lacking. Here, we demonstrate that Cetobacterium somerae (C. somerae), enriched by mannose supplementation under high‐fat diet conditions, convert arginine into putrescine.
Delong Meng +10 more
wiley +1 more source
Evolvability of Chaperonin Substrate Proteins [PDF]
Molecular chaperones ensure that their substrate proteins reach the functional native state, and prevent their aggregation. Recently, an additional function was proposed for molecular chaperones: they serve as buffers (_capacitors_) for evolution by ...
Emanuele Raineri +3 more
core +1 more source
The role of the gut microbiome in the regulation of high‐altitude adaptation
This study is the first to elucidate mechanisms of high‐altitude adaptation from the perspective of the rumen ecosystem by using indigenous yaks and Holstein cows that have lived at high altitude since birth as comparative models. Through a systematic comparison of their rumen ecology using multi‐omics approaches—including rumen metagenomics ...
Xinyu Zhang +6 more
wiley +1 more source
Expression of tfx and sensitivity to the rhizobial peptide antibiotic trifolitoxin in a taxonomically distinct group of alpha-proteobacteria including the animal pathogen Brucella abortus [PDF]
Eric W. Triplett +2 more
openalex +1 more source
Abstract Background Although periodontitis and oral microbiota are linked to cardiometabolic diseases (CMD), it is unclear if they similarly predict CMD mortality. We compared the predictive ability of salivary microbiota and periodontal disease measures for CMD mortality in the National Health and Nutrition Examination Survey (NHANES).
Hamdi S. Adam +6 more
wiley +1 more source

