Results 171 to 180 of about 31,301 (210)
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The course of proteolysis of lysozyme
Archives of Biochemistry and Biophysics, 1956Abstract The course of proteolysis of lysozyme by chymotrypsin, trypsin, papain at three pH's, and pepsin is reported with tabulation of progressive exposure of 15 N-residue types and 12 C-residue types. A marked similarity in pattern of hydrolysis has been observed.
S W, FOX, T L, HURST
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Stimulation of proteolysis on calmodulin
Life Sciences, 1990The proteolysis of calmodulin by fungal protease (type XIX) was greatly enhanced in the presence of dGTP and MS2 RNA. Whereas, only moderate proteolytic activation on bacterial proteases (type XXVI) was observed in the presence of MS2 RNA. No appreciable proteolysis of calmodulin by bacterial protease (type IX) was observed.
W N, Kuo +5 more
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Proteases and proteolysis in the lysosome
Experientia, 1992Proteins sequestered by a non-selective bulk process within the lysosomes turn over with an apparent half-life of about 8 minutes and this rapid lysosomal proteolysis is initiated by endopeptidases, in particular by the cathepsins D and L. We describe also the cathepsins B and H which show mainly exopeptidase and only low endopeptidase activity ...
P, Bohley, P O, Seglen
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Protein oxidation and proteolysis
bchm, 2006Abstract One of the hallmarks of chronic or severe oxidative stress is the accumulation of oxidized proteins, which tend to form high-molecular-weight aggregates. The major proteolytic system responsible for the removal of oxidized cytosolic and nuclear proteins is the proteasome.
Nicolle, Bader, Tilman, Grune
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Ozone and Pulmonary Proteolysis
Annals of Internal Medicine, 1970Excerpt To the editor: In their editorial on antitrypsin deficiency Falk and Briscoe (Ann Intern Med72:427-429, 1970) point out that intrapulmonary proteolysis might be due to either decreased inhi...
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Biochemical and Biophysical Research Communications, 1989
The calpain-induced proteolysis of tau associated with twice-cycled microtubules or from a total brain heat-stable fraction was studied. Twice-cycled microtubule tau was rapidly hydrolyzed by calpain. In contrast, tau purified from the total brain heat-stable fraction was very resistant to degradation by calpain.
G V, Johnson, R S, Jope, L I, Binder
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The calpain-induced proteolysis of tau associated with twice-cycled microtubules or from a total brain heat-stable fraction was studied. Twice-cycled microtubule tau was rapidly hydrolyzed by calpain. In contrast, tau purified from the total brain heat-stable fraction was very resistant to degradation by calpain.
G V, Johnson, R S, Jope, L I, Binder
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Proteolysis and Sterol Regulation
Annual Review of Cell and Developmental Biology, 2002▪ Abstract  The mammalian cell continuously adjusts its sterol content by regulating levels of key sterol synthetic enzymes and levels of LDL receptors that mediate uptake of cholesterol-laden particles. Control is brought about by sterol-regulated transcription of relevant genes and by regulated degradation of the committed step enzyme HMG-CoA ...
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Proteolysis in Bacterial Sporulation
1980Publisher Summary Endospore formation and germination in various Bacillus species provide attractive experimental models for the study of cellular differentiation. These bacteria offer the advantages of easy cultivation and physiological manipulation, the possibility of genetic analysis, and a well-defined, relatively simple unicellular ...
M R, Maurizi, R L, Switzer
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Measuring Proteolysis in Mitosis
2009The targeted destruction of key regulators helps to drive the cell cycle. Here we describe a quantitative assay to measure destruction of different regulators in mitotic cells. This assay uses GFP-tagged substrates and time-lapse fluorescence microscopy of single cells to pinpoint the timing of destruction of different substrates at different stages in
Catherine, Lindon, Barbara, Di Fiore
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Hsp70s and lysosomal proteolysis
Experientia, 1994Confluent cultured cells activate a lysosomal pathway of polypeptide breakdown in response to withdrawal of serum growth factors. The substrates for this proteolytic pathway are a restricted class of cytosolic polypeptides containing peptide sequences biochemically related to lysine-phenylalanine-glutamate-arginine-glutamine, or, in single amino acid ...
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