Results 191 to 200 of about 183,121 (297)

Lysosomal Cathepsin S Escape Facilitates Near Infrared Light‐Triggered Pyroptosis Via an Antibody‐Indocyanine Green Conjugate

Advanced Science, EarlyView.
ICAM1 antibody‐bound ICG triggers tumor‐specific, caspase‐1‐independent pyroptosis via CTSS‐mediated GSDMD cleavage, activates antitumor immunity, and synergizes with anti–PD‐1 therapy, offering a non‐apoptotic strategy to overcome resistance in cancer treatment.
Fan Chen, Xue‐Fei Tian, Teng Yang, Yu‐Jie Dai, Da‐Yuan Chen, Hong‐Bo Chen, Takaya Shimura, Xin‐Fang Li, Chu‐Lin Sha, Qing Ji, Jun Cao, Mei‐Yu Fang, Jin‐Biao Shang, Jian‐Min Fang, Ye Lu, Wei‐Hui Zheng, Peng Guo, Wei‐Hong Tan   +17 more
wiley   +1 more source

Hypoxia Induces Extensive Protein and Proteolytic Remodeling of the Cell Surface in Pancreatic Adenocarcinoma (PDAC) Cell Lines. [PDF]

J Proteome Res
Lui I, Schaefer K, Kirkemo LL, Zhou J, Perera RM, Leung KK, Wells JA.   +6 more
europepmc   +1 more source

Proteolysis of the major capsid protein T4 bacteriophage polyheads limited by quaternary structure.

, 1978
Albert Boosman
openalex   +1 more source

Advancements in DNA‐Driven Precision Modulation of Cell Surface Receptor for Programmable Cellular Functions

Advanced Science, EarlyView.
DNA‐Based Genetic and Non‐Genetic Tools for Receptor Engineering. This review highlights recent advances in DNA‐based strategies for receptor engineering, including genetic approaches like domain fusion and site‐directed mutagenesis, as well as non‐genetic methods using functional nucleic acids, DNA nanostructures, and dynamic DNA reactions.
Hexin Nan, Ming Cai, Yiyu Wang, Hong‐Hui Wang, Zhou Nie   +4 more
wiley   +1 more source

Effect of dry ice addition and wilting on the rates of fermentation and proteolysis in ensiled alfalfa. [PDF]

Sci Rep
Borsuk-Stanulewicz M, Białobrzewski I, Przemieniecki SW, Purwin C.   +3 more
europepmc   +1 more source

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

, 1977
Don W. Cleveland, S G Fischer, Marc W. Kirschner, Ulrich K. Laemmli   +3 more
openalex   +1 more source

Genetic Impacts on the Structure and Mechanics of Cellulose Made by Bacteria

Advanced Science, EarlyView.
A genetic mutation in a protease of a cellulose‐overproducing evolved bacterium significantly affects the proteome, structure, and mechanical properties of bio‐fabricated cellulose pellicles. By overexpressing synthase proteins that build the cellulose‐forming biological machinery of the cell, the evolved bacterium generates dense, stiff, and strong ...
Julie M. Laurent, Mathias Steinacher, Anton Kan, Maximilian Ritter, Mario Leutert, Siiri Bienz, David Häberlin, Naresh Kumar, André R. Studart   +8 more
wiley   +1 more source

Hijacking the MDM2 E3 Ligase with Novel BRD4-Targeting Proteolysis-Targeting Chimeras in Pancreatic Cancer Cells. [PDF]

Chembiochem
Ficu MP, Niculescu-Duvaz D, Aljarah M, Kershaw CS, Springer CJ.   +4 more
europepmc   +1 more source

Measurement of Proteolysis in Natural Waters [PDF]

, 1979
Jack E. Little, Robert E. Sjogren, Gerald Carson   +2 more
openalex   +1 more source

A ROS‐Responsive Dual‐Targeting Drug Nanocarrier Serving as a GSI Synergist and Ferroptosis Sensitizer for T‐Cell Acute Lymphoblastic Leukemia

Advanced Science, EarlyView.
A self‐assembling nanotherapeutic strategy is designed—CD38‐PHD/G‐NPs, which released γ‐secretase inhibitor first, followed by adaptive dihydroartemisnin release in response to elevated reactive oxygen species levels. This controlled, sequential release strategy maximizes the synergistic anti‐leukemic efficacy of two agents with distinct mechanisms of ...
Ruinan Jia, Yang Liu, Jilong Xiao, Yuan Xia, Xin Zhao, Huixian Ma, Jingjing Ye, Zhiyue Zhang, Tao Sun, Chunyan Ji   +9 more
wiley   +1 more source