Results 231 to 240 of about 442,290 (346)

Microbial and metabolic responses of maize silage to leaf blight: implications for fermentation and protein stability. [PDF]

BMC Plant Biol
Xu L, Lv X, Lu X, Zhang X, Liu J, Meng Y, Wu D.   +6 more
europepmc   +1 more source

Immunoregulatory roles of versican proteolysis in the myeloma microenvironment.

Blood, 2016
C. Hope, Simon J. Foulcer, J. Jagodinsky, Sarah X. Chen, J. L. Jensen, Sanjay S. Patel, C. Leith, I. Maroulakou, N. Callander, S. Miyamoto, P. Hematti, S. Apte, F. Asimakopoulos   +12 more
semanticscholar   +1 more source

A Soft Matrix Microenvironment Promotes Laterally Spreading Tumors via Oxidative Phosphorylation‐Dependent Cell Adhesion

Advanced Science, EarlyView.
Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong, Jingyi Lu, Haopeng Li, Jun Zhong, Xiaobei Luo, Yiyi Hu, Xianfei Wang, Pengfei Wang, Yanning Zhang, Zhenjiang Wang, Qiuhua Lai, Zhenyu Chen, Wenting Mi, Wang Tin San‐to, Weize Li, Shuping Tan, Qihong Cheng, Ruijia Li, Yida Nie, Side Liu, Bing Huang, Zelong Han   +21 more
wiley   +1 more source

Mechanisms of protein degradation in atrophying muscles: What have we learned during the past decade? [PDF]

J Biol Chem
Shemer S.
europepmc   +1 more source

Tumor‐Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T‐Cell Infiltration and Limiting Myeloid Cell‐Mediated Immunosuppression

Advanced Science, EarlyView.
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li, Lan Wang, Zihao Zhang, Chunmei Qian, Ning Li, Wei Huang, Qian Ba, Xiaojian Liu, Mayu Sun   +8 more
wiley   +1 more source

Proteolytic Activity of Human Lymphoid Tumor Cells.Correlation with Tumor Progression

Clinical and Developmental Immunology, 2000
Angelo Vacca, Domenico Ribatti, Roberto Ria, Antonio Pellegrino, Michele Bruno, Francesca Merchionne, Franco Dammacco   +6 more
doaj   +1 more source

Rapid and Label-Free Structural Proteomics Using One-Step Swift Trypsin LiP-MS. [PDF]

ACS Omega
Miyashita Y, Konno R, Ogasawara S, Okuda Y, Takamuku Y, Moriya T, Saito T, Murata T, Ohara O, Kawashima Y.   +9 more
europepmc   +1 more source

Clotting and other plasma factors in experimental endotoxemia: inhibition of degradation by exogenous proteinase inhibitors. [PDF]

, 1981
Fritz, Hans, Jochum, Marianne, Ruckdeschl, G., Schießler, Hans, Selbmann, H. K., Witte, J.   +5 more
core   +1 more source

Mitochondrial Enzymes Mimetic Ultrasmall Palladium Nanozymes Prevent Senescence and Neurodegeneration Through Metabolic Reprogramming

Advanced Science, EarlyView.
Simply constructed polyvinylpyrrolidone (PVP) modified palladium nanoparticles (PdP NPs) as cytochrome c oxidase (CcO) and superoxide dismutase (SOD) mimic are promising multifunctional nanoreactors to boost mitochondrial respiration chain function and refine homeostasis via regulation of mitochondrial dynamics and proteostasis sensor UPRmt, which ...
Wenshu Cong, Haiming Jing, Zinan Li, Wenjing Zhang, Nan Zhang, Yingqiu Xie, Shan Gao, Yuanyu Huang, Junyu Ning   +8 more
wiley   +1 more source

Indirect ubiquitination independent of endogenous ubiquitination machinery for targeted protein degradation. [PDF]

Commun Chem
Furuhata T, Yoshida K, Fujita R, Miyamoto J, Moriyama C, Masuda-Ozawa T, Tsuchiya H, Saeki Y, Okamoto A.   +8 more
europepmc   +1 more source