Results 181 to 190 of about 416,903 (305)

Phosphorylation of enteroviral 2Apro at Ser/Thr125 benefits its proteolytic activity and viral pathogenesis. [PDF]

open access: yesJ Med Virol, 2023
Wang Y   +12 more
europepmc   +1 more source

Integrative Approaches to Treating Cellular Senescence in Kidney Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Cellular senescence in the kidney plays a crucial role in the progression of acute kidney injury and chronic kidney disease. Therapeutic approaches targeting senescent cells, such as small molecule senolytic and senomorphic drugs, display efficacy in preclinical models.
Tomoka Misawa   +3 more
wiley   +1 more source

PROTEOLYTIC ACTIVITY OF PITUITARY EXTRACTS

open access: yesJournal of Biological Chemistry, 1951
E, ADAMS, E L, SMITH
openaire   +2 more sources

Proteinases [PDF]

open access: yes, 1993
Fritz, Hans   +5 more
core   +1 more source

ZBTB21 Is a Dual Suppressor of Pyroptosis and MHC‐I Antigen Presentation That Promotes Tumor Immune Evasion

open access: yesAdvanced Science, EarlyView.
ZBTB21 is a transcription factor that epigenetically suppresses pyroptosis and MHC‐I antigen presentation, enabling tumor immune evasion. Genetic ablation of ZBTB21 activates pyroptotic cell death and enhances antigen presentation, recruiting CD8+ T cells to overcome immune checkpoint blockade resistance.
Lei Zhao   +12 more
wiley   +1 more source

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