Results 181 to 190 of about 264,068 (308)

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

open access: yesAdvanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li   +7 more
wiley   +1 more source

Regulation of proteolytic enzyme activity in Lactococcus lactis.

open access: yes, 1996
Two different Lactococcus lactis host strains, L. lactis subsp. lactis MG1363 and L. lactis subsp. cremoris SK1128, both containing plasmid pNZ521, which encodes the extracellular serine proteinase (PrtP) from strain SK110, were used to study the medium ...
Hugenholtz, J., Meijer, W., Marugg, J.D.
core  

Proteolytic Activities of Human Mycoplasmas [PDF]

open access: yesJapanese Journal of Microbiology, 1973
T, Watanabe, K, Mishima, T, Horikawa
openaire   +2 more sources

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

open access: yesAdvanced Science, EarlyView.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li   +13 more
wiley   +1 more source

Ultrahigh-throughput screening of environmental bacteria for proteolytic activity using droplet-based microfluidics. [PDF]

open access: yesAppl Environ Microbiol
Nakamura A   +6 more
europepmc   +1 more source

Covalent Reprogramming of Kinase Binders to Modulate Protein Abundance

open access: yesAdvanced Science, EarlyView.
Electrophilic remodeling of a broad‐spectrum kinase binder reveals how subtle chemical changes reprogram protein fate. An acrylamide analog of a multi‐kinase binder selectively stabilizes Aurora kinase A (AURKA) by suppressing its ubiquitination, while a short‐linker variant converts this stabilizer into a degrader.
Chen Mozes   +4 more
wiley   +1 more source

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