Results 51 to 60 of about 6,061,554 (251)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Effect of auxin (iaa) upon the proteolytic system in differentiating secondary xylem of pine (Pinus sylvestris L.)

open access: yesActa Societatis Botanicorum Poloniae, 2014
Effects of decapitation and IAA on proteolytic activity were studied in main stem of 4-7 year-old Pinus sylvestris trees. Proteolytic activity in the extract from differentiating secondary xylem was found to be totally reduced in decapitated 2-3 year-old
Krzysztof J. Rakowski   +1 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Soil-Derived Endospore-Forming Bacillus Bacteria Producing Protease

open access: yesJRST: Jurnal Riset Sains dan Teknologi
Proteases are widely utilized in many industries, including waste treatment, textiles, detergents, food processing, and medicines. This encourages researchers to discover novel sources of these enzymes.
Mazidah Noer Inayah   +2 more
doaj   +1 more source

Human Neutrophil Elastase Proteolytic Activity in Ulcerative Colitis Favors the Loss of Function of Therapeutic Monoclonal Antibodies [PDF]

open access: yes, 2020
Purpose: Proteases play an essential role in the pathophysiology of inflammatory bowel disease (IBD), contributing to the intestinal mucosal lesions through the degradation of the extracellular matrix and alteration of the barrier function.
Jones, Samantha   +17 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Mise en évidence d'une production de protéases exocellulaires par les levures au cours de la fermentation alcoolique du moût de raisin

open access: yesOENO One, 1980
La durée d'activité très limitée dans le temps des protéases du raisin est confirmée en vinification en blanc, mais une nouvelle activité protéolytique peut être caractérisée à 37 °C et à pH 3,7 dans le moût au cours de la fermentation alcoolique.
Michel Feuillat   +3 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

The rodents (mice) burrowing activity in the restoring of soil proteolytic activity under conditions of the technogenic pollution

open access: yesVìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ, 2005
The research for rodents (mice) burrowing activity finding on the soil proteolytic one was made in the natural environment. It was shown that under conditions of heavy metals pollutions the proteolytic activity level within burrows was higher than the ...
T. A. Zamesova
doaj   +1 more source

Home - About - Disclaimer - Privacy