Results 151 to 160 of about 281,302 (344)

THE RELEASE OF PROTEIN, LIPID AND POLYSACCHARIDE COMPONENTS OF THE ARTERIAL ELASTICA BY PROTEOLYTIC ENZYMES AND LIPID SOLVENTS [PDF]

, 1962
C. W. M. Adams, O. B. Bayliss
openalex   +1 more source

Cleavage‐Resistant CYLD Protects Against Autoimmune Hepatitis

Advanced Science, EarlyView.
Proteolytic cleavage of the deubiquitinase CYLD emerges as a critical driver of autoimmune hepatitis. TNFα‐induced CYLD loss in macrophages amplifies S100A9‐triggered MAPK activation, leading to excessive chemokine production and hepatic inflammation. Pharmacological inhibition of MEK signaling effectively attenuates experimental disease, highlighting ...
Han Liu, Chen Su, Jianling Liu, Mingyan Xing, Xiaoxia Wu, Lingxia Wang, Xiaoming Zhao, Hanwen Zhang, YangYang Xie, YangYang Wang, Hong Li, Yu Li, Ming Li, Haibing Zhang   +13 more
wiley   +1 more source

Proteolytic Enzyme Activities of Bromelain, Ficin, and Papain from Fruit By-Products and Potential Applications in Sustainable and Functional Cosmetics for Skincare

Applied Sciences
Enzyme peels are an emerging and effective cosmetic technique for controlled skin exfoliation. Naturally occurring proteolytic enzymes such as bromelain, ficin, and papain have gained increasing attention as promising cosmetic and cosmeceutical ...
Maria Venetikidou, Eleni Lykartsi, Theodora Adamantidi, Vasileios Prokopiou, Anna Ofrydopoulou, Sophia Letsiou, Alexandros Tsoupras   +6 more
doaj   +1 more source

Inhibition of Proteolytic Enzymes from Pseudomonas fluorescens ATCC 948 and Angiotensin I-Converting Enzyme by Peptides from Zein, Hordein, and Gluten Hydrolysates

, 1997
Marco Gobbetti, E. Smacchi, Aldo Corsetti, Michele Bellucci   +3 more
openalex   +2 more sources

CRISPR in MOF Formulation with Enhanced Stability, Activity, and Altered PAM Specificity for Broad‐Spectrum Diagnosis of Bacterial Sepsis

Advanced Science, EarlyView.
CRISPR‐FLEXMO (CRISPR with flexible PAM in MOF encapsulation) integrates a PAM‐relaxed Cas12a K607R enzyme with a manganese‐coordinated MOF for broad‐spectrum diagnosis of bacterial sepsis. The MOF enhances activity and preserves functionality under heat, solvent, and chaotropic stress, supporting long‐term room‐temperature storage.
Tathagata Pal, Zilong Liu, Meera G. Nair, Juhong Chen   +3 more
wiley   +1 more source

Effect of proteolytic enzymes and insulin sensitiser in treatment of joint osteoarthritis in diabetic patients [PDF]

Yasir Atia, Safaa Salman Mezban Al-thamiree, Shatha Salah, Zaid Al‐Attar   +3 more
openalex   +1 more source

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

Advanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong, Yulong Li, Hui Liang, Zumei Wu, Shiqun Wang, Yichao Wang, Jieyu Xu, Yanning Lan, Maohua Cai, Guangzhao Pan, Haiyan Yang, Kai Miao, Zhe‐Sheng Chen, Fangfang Tao, Xuelei Ma, Jiang‐Jiang Qin   +15 more
wiley   +1 more source

Meat quality, post-mortem proteolytic enzymes, and myosin heavy chain isoforms of different Thai native cattle muscles. [PDF]

Anim Biosci, 2021
Chaosap C, Sivapirunthep P, Sitthigripong R, Tavitchasri P, Maduae S, Kusee T, Setakul J, Adeyemi K.   +7 more
europepmc   +1 more source

A high‐order structure of plant storage proprotein allows its second conversion by an asparagine‐specific cysteine protease, a novel proteolytic enzyme [PDF]

, 1993
Masayoshi Muramatsu, Chikafusa Fukazawa
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Antimicrobial Effect of a Proteolytic Enzyme From the Fruits of Solanum granuloso-leprosum (Dunal) Against Helicobacter pylori

, 2021
Ángel Gabriel Salinas Ibáñez, Diego Vallés, Mauricio Adaro, S Barberis, Alba Edith Vega   +4 more
openalex   +1 more source