Results 231 to 240 of about 2,254,706 (376)
Separation of the Proteolytic and Streptolytic Components of a Streptomyces albus Enzyme Preparation and Their Effect on Streptococcal Cells [PDF]
Juanita P. Bray, J A Bass
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Lipopolysaccharide (LPS) stimulates the production of succinic acid in lung tissue, which promotes macrophages endocytosis and the formation of multivesicular bodies (MVBs). These MVBs release profibrotic extracellular vesicles (EVs), facilitating the transfer of integrin beta1 (ITGβ1) transfer and subsequently activating fibroblasts, thereby ...
Wenyu Yang +10 more
wiley +1 more source
The Effect of Proteolytic Enzymes on E. coli Phages and on Native Proteins [PDF]
John H. Northrop
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Nestin localizes to the mitochondrial IMS through its MTS and the TOM20 import machinery. Within the mitochondria, Nestin interacts with Mic60 via its C‐terminal Tail3 domain. Loss of mitochondrial Nestin disrupts cristae architecture, leading to mitochondrial swelling, bioenergetic dysfunction, and ultimately the senescence of hMSCs.
Hainan Chen +14 more
wiley +1 more source
Characteristics of an Endocellular Proteolytic Enzyme System of Streptococcus Lactis
Wouter Zant, F.E. Nelson
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Inhibition of Tumor Lipogenesis and Growth by Peptide‐Based Targeting of SREBP Activation
A peptide that replicates the amino acid sequence in Insig1/2 loop 1 inhibits the IGF1‐induced interaction between PCK1 and Insig1/2, PCK1‐mediated phosphorylation of Insig1/2, and SREBP activity‐dependent lipid synthesis. Administration of the LNP‐Insig1/2 loop 1 peptide effectively attenuates tumor growth and sensitizes tumors to the antitumor effect
Shudi Luo +10 more
wiley +1 more source
Crucial Involvement of IL-6 in Thrombus Resolution in Mice via Macrophage Recruitment and the Induction of Proteolytic Enzymes. [PDF]
Nosaka M +8 more
europepmc +1 more source

