Results 151 to 160 of about 538,471 (385)

MAPU 2.0: high-accuracy proteomes mapped to genomes [PDF]

, 2008
Florian Gnad, Mario Oroshi, Ewan Birney, Matthias Mann   +3 more
openalex   +1 more source

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

High-throughput method for mammalian protein function | The effect of antimitotic chemotherapy drugs on mitotic proteins | Proteome map of Arabidopsis thaliana | Figuring out in vivo protein–protein interactions | How ibuprofen may protect against Alzheimer's disease | Identifying wheat allergens [PDF]

, 2008

openalex   +1 more source

Structural Analysis of Mammalian Protein Phosphorylation at a Proteome Level

, 2021
Altuğ Kamacıoğlu, Nurcan Tunçbağ, Nurhan Özlü   +2 more
openalex   +1 more source

NPC1 controls TGFBR1 stability in a cholesterol transport-independent manner and promotes hepatocellular carcinoma progression

Nature Communications
Niemann-Pick disease type C protein 1 (NPC1), classically associated with cholesterol transport and viral entry, has an emerging role in cancer biology.
Shuangyan Li, Lishan Yan, Chaoying Li, Lijuan Lou, Fengjiao Cui, Xiao Yang, Fuchu He, Ying Jiang   +7 more
doaj   +1 more source

Pre‐Administration of Akkermansia Muciniphila Prevents the Development of Severe Acute Graft‐Versus‐Host Disease in Systemic Organs

Advanced Science, EarlyView.
Akkermansia muciniphila, a next‐generation probiotic, alleviates acute graft‐versus‐host disease (aGvHD) following allogeneic hematopoietic stem cell transplantation (HSCT) by providing protective effects across multiple organs. Pre‐colonization with A.
Jeong‐Eun Han, Dae‐Seong Lee, Su‐Won Jeong, Ji‐Hyun Yun, Seomin Kang, Seoyoung Jang, EunAh Lee, Ju Hye Baek, Che Ok Jeon, Jin‐Woo Bae   +9 more
wiley   +1 more source

Plasma proteome alterations in prediabetic, obese Zucker rats – possible cardiovascular risk implications

, 2022
Justyna Totoń‐Żurańska, Lucia Balážová, Katarína Kršková, Beata Bujak-Giżycka, Štefan Zórad, Rafał Olszanecki, Maciej Suski   +6 more
openalex   +2 more sources

Regulation of lipoprotein processing by GPNMB in foamy macrophages: potential therapeutic targets for atherosclerosis

Nature Communications
The formation of foamy macrophages is often considered a pathological hallmark of atherosclerosis, but the underlying mechanisms remain elusive. Herein, we demonstrated that the transcription factor TFEC could upregulate the expression of Glycoprotein ...
Junqi Wang, Liming Peng, Huan Wang, Di Liu, Wenting Yang, Fang Yan, Dianyuan Zhao, Chunhua Zhang, Ziliang He, Xiao-Ping Chen, Li Tang   +10 more
doaj   +1 more source

An integrated bioinformatics platform for investigating the human E3 ubiquitin ligase-substrate interaction network

Nature Communications, 2017
Protein stability modulation by E3 ubiquitin ligases is an important layer of functional regulation, but screening for E3 ligase-substrate interactions is time-consuming and costly.
Yang Li, Ping Xie, Liang Lu, Jian Wang, Lihong Diao, Zhongyang Liu, Feifei Guo, Yangzhige He, Yuan Liu, Qin Huang, Han Liang, Dong Li, Fuchu He   +12 more
doaj   +1 more source

Plasma proteome analyses in individuals of European and African ancestry identify cis-pQTLs and models for proteome-wide association studies

Nature Genetics, 2022
Jingning Zhang, Diptavo Dutta, A. Köttgen, A. Tin, P. Schlosser, Morgan E. Grams, Benjamin Harvey, B. Yu, E. Boerwinkle, J. Coresh, N. Chatterjee   +10 more
semanticscholar   +1 more source