Results 191 to 200 of about 205,179 (309)

A DNP‐Supported Solid‐State NMR Approach to Study Nucleic Acids In Situ Reveals Berberine‐Stabilized Hoogsteen Structures in Mitochondria

open access: yesAngewandte Chemie, EarlyView.
Mitochondria are vital for energy production and rely on intricate nucleic acid structures to regulate gene expression. Using DNP‐ssNMR (dynamic nuclear polarization solid‐state NMR), we observed G‐quadruplex formation in intact mitochondria treated with berberine.
Michaela Dzurov Krafčíková   +8 more
wiley   +2 more sources

ProSIMSIt: The Best of Both Worlds in Data-Driven Rescoring and Identification Transfer. [PDF]

open access: yesJ Proteome Res
Hamood F   +5 more
europepmc   +1 more source

Human proteome enhancement: High-recovery method and improved two-dimensional map of colostral fat globule membrane proteins [PDF]

open access: bronze, 2001
Stefania Quaranta   +9 more
openalex   +1 more source

Longitudinal Proteomic Profiling of Cognition across an Aerobic Exercise Intervention

open access: yesAnnals of Neurology, EarlyView.
The physiological basis of cognitive decline remains largely uncharacterized. We identified a protein panel signature, in living humans, that correlates to improvement in neurocognition over a period of 5 years. Our signature is composed of complement proteins, coagulation cascade, and extracellular matrix regulators.
Alison M. H. Donald   +16 more
wiley   +1 more source

Electrophoretic detection of black market myostatin propeptide

open access: yesDrug Testing and Analysis, Volume 14, Issue 11-12, Page 1812-1824, November-December 2022., 2022
Of the 12 black market products investigated, only nine contained the target protein among dozens of other proteins. In the remaining ones, small growth hormone‐related peptides were found by mass spectrometry (e.g., tesamorelin). A shotgun proteomics approach revealed that all nine products contained full length GST‐tags.
Christian Reichel   +2 more
wiley   +1 more source

Roadmap to Nanomedical Applications: Nanotoxicology and In Vitro Guidelines for Lanthanide‐Doped Luminescence Nanothermometers

open access: yesAdvanced NanoBiomed Research, EarlyView.
Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska   +2 more
wiley   +1 more source

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