Results 221 to 230 of about 538,471 (385)

Deorphanization of the human leukocyte tyrosine kinase (LTK) receptor by a signaling screen of the extracellular proteome [PDF]

, 2014
Hongbing Zhang, Lily Pao, Aileen J. Zhou, Arthur D. Brace, Robert Halenbeck, Amy W. Hsu, Thomas L. Bray, Kevin Hestir, Elizabeth Bosch, Ernestine Lee, Gang Wang, Haixia Liu, Brian Wong, W. Michael Kavanaugh, Lewis T. Williams   +14 more
openalex   +1 more source

The koala (Phascolarctos cinereus) prostate: a proteomic perspective on gland segmentation. [PDF]

Biol Reprod
Campbell Y, Johnston SD, Palmieri C, Pini T.   +3 more
europepmc   +1 more source

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

Advanced Science, EarlyView.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan, Fengmei Zhang, Jiayan Zhong, Qian Gong, Nana Geng, Biao Kuang, Qiumei Lan, Miao Yi, Qiqi Zeng, Cheng Chen, Mengtian Fan, Chunliang Zhao, Deping Zeng, Yu Du, Mao Nie, Zhibiao Wang, Fengjin Guo   +16 more
wiley   +1 more source

Author response: Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice

, 2022
Vasiliki‐Ilya Gargareta, Josefine Reuschenbach, Sophie B. Siems, Ting Sun, Lars Piepkorn, Carolina Mangana, Erik Späte, Sandra Goebbels, Inge Huitinga, Wiebke Möbius, Klaus‐Armin Nave, Olaf Jahn, Hauke Werner   +12 more
openalex   +1 more source

The Proteome of <i>Dictyostelium discoideum</i> Across Its Entire Life Cycle Reveals Sharp Transitions Between Developmental Stages. [PDF]

Proteomes
Banu S, Anusha PV, Beltran-Alvarez P, Idris MM, Wollenberg Valero KC, Rivero F.   +5 more
europepmc   +1 more source

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

Advanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang, Binbin Zhao, Min Jia, Yan Zhao, Ye Lu, Wenyu Xi, Ziyu Zhu, Xiaojuan Gong, Qingyan Ma, Yuan Gao, Yijie Guo, Pan Li, Feng Zhu, Shuguang Wei, Xiancang Ma, Yunpeng Wang   +15 more
wiley   +1 more source

Nitric oxide required for transition to slower hepatic protein synthesis rates during long-term caloric restriction. [PDF]

J Clin Invest
Palacios HH, Cao E, Cahill A, Mohamad H, Hellerstein MK.   +4 more
europepmc   +1 more source

Mass-spectrometry-based draft of the Arabidopsis proteome

Nature, 2020
J. Mergner, Martin Frejno, M. List, Michael Papacek, Xia Chen, Ajeet Chaudhary, Patroklos Samaras, Sandra Richter, Hiromasa Shikata, Maxim Messerer, D. Lang, Stefan Altmann, P. Cyprys, Daniel P. Zolg, Toby Mathieson, M. Bantscheff, R. Hazarika, Tobias Schmidt, C. Dawid, A. Dunkel, T. Hofmann, S. Sprunck, Pascal Falter-Braun, F. Johannes, Klaus F. X. Mayer, G. Jürgens, Mathias Wilhelm, J. Baumbach, E. Grill, K. Schneitz, C. Schwechheimer, B. Kuster   +31 more
semanticscholar   +1 more source

Discovery of a Novel DNMT1 Inhibitor with Improved Efficacy in Treating β‐Thalassemia

Advanced Science, EarlyView.
Context of Research: β‐thalassemia affects millions worldwide. DNMT inhibitors are effective HbF‐inducers that benefit patients with β‐thalassemia. Existing DNMT inhibitors are not approved for β‐thalassemia treatment due to dose‐limiting toxicity.What We Find: DMT207 traps DNMT1 into helix‐kinked inactive conformation and enhances its interaction with
Yijie Shen, Jiale Wei, Shibing Tang, Dongliang Wu, Liangyi Zong, Shuyuan Ma, Qing Xiong, Ruijie Gong, Siyuan Xu, Chuxuan Peng, Qin Feng, Songchen Liu, Qitong Liu, Yuhua Ye, Quan Zhao, Cheng Luo, Peng Huang, Zhihai Li, Xiangqian Kong, Xianjiang Lan   +19 more
wiley   +1 more source

Proteome Analysis Using Gel‐LC‐MS/MS

, 2019
Aaron R. Goldman, Lynn A. Beer, Hsin‐Yao Tang, Peter Hembach, Delaine Zayasbazan, David W. Speicher   +5 more
openalex   +2 more sources