Results 141 to 150 of about 591,485 (302)

Mining whole sample mass spectrometry proteomics data for biomarkers: an overview

, 2009
In this paper we aim to provide a concise overview of designing and conducting an MS proteomics experiment in such a way as to allow statistical analysis that may lead to the discovery of novel biomarkers.
Thomas, Lyn C., Bennell, J., McDonald, R, O'Connor, David, Skipp, Paul, Potts, Chris N.   +5 more
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Proteomic analysis of cell models of ovarian cancer tumour suppression [PDF]

, 2010
Epithelial ovarian cancer (EOC) is the most common form of gynaecological malignancy in the developed world. Identifying molecular markers of disease may provide novel approaches to screening and could enable targeted treatment and the design of novel
Sinclair, J.R.
core  

GC-MS Combined with Proteomic Analysis of Volatile Compounds and Formation Mechanisms in Green Teas with Different Aroma Types

Foods
Aroma is one of the key factors for evaluating the quality of green tea. A tender aroma (NX) and floral-like aroma (HX) are two types of high-quality aroma of green tea.
Xiaojun Niu, Cun Ao, Jizhong Yu, Yun Zhao, Haitao Huang   +4 more
doaj   +1 more source

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

Proceedings of the National Academy of Sciences of the United States of America, 2016
J. Kowal, Guillaume Arras, Marina Colombo, M. Jouve, Jakob Paul Morath, Bjarke Primdal-Bengtson, F. Dingli, D. Loew, M. Tkach, C. Théry   +9 more
semanticscholar   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

COMPARATIVE IMMUNOPROTEOMICS OF HELYCOBACTER PYLORI FOR THE IDENTIFICATION OF GASTRIC ATROPHY PROGNOSTIC MARKERS.

, 2006
Helicobacter pylori is a Gram-negative bacterium which causes ulcer, atrophic gastritis, adenocarcinoma, or mucosa-associated lymphoid tissue lymphoma. A comparative proteomic and immunoproteomic analysis was chosen to identify the antigenic patterns of ...
Renzone G, Annibale B, Santucci A, Laner E, Figura N, Mini R, Braconi D, Scaloni A, Bernardini G   +8 more
core  

Multi-omics profiling reveals peripheral blood biomarkers of multiple sclerosis: implications for diagnosis and stratification

Frontiers in Pharmacology
BackgroundMultiple sclerosis (MS), a chronic autoimmune disorder marked by demyelination in the central nervous system, is exceptionally uncommon in China, and remains poorly understood in terms of its peripheral blood manifestations.MethodsWe conducted ...
Qinming Zhou, Qinming Zhou, Qinming Zhou, Zuoquan Xie, Lu He, Lu He, Guangqiang Sun, Huanyu Meng, Huanyu Meng, Zhiyu Luo, Yuan Feng, Xingkun Chu, Liang Li, Jing Zhang, Yong Hao, Meiyu Geng, Meiyu Geng, Xiang Zhang, Xiang Zhang, Sheng Chen, Sheng Chen, Sheng Chen   +21 more
doaj   +1 more source