Results 191 to 200 of about 662,616 (328)

A Microphysiological Interface of Skeletal Myobundles and Inflamed Adipose Tissue for Recapitulating Muscle Dysfunction in an Obese Microenvironment

Advanced Healthcare Materials, EarlyView.
A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim, Tianxin Cao, Zhengpeng Wan, Jaesang Kim, Zhuxuan Li, Legairre A. Radden II, Rakesh Santhanam, Eunkyung Clare Ko, Tatsuya Osaki, Sarah Spitz, Hyunmin Moon, Maria Proestaki, Seokbeom Roh, Gyudo Lee, Jessie S. Jeon, Curtis R. Warren, Roger D. Kamm   +16 more
wiley   +1 more source

Quantitative Proteomics [PDF]

Analytical Chemistry, 2013
John R, Yates, Michael P, Washburn
openaire   +2 more sources

The ProteomeXchange consortium in 2026: making proteomics data FAIR. [PDF]

Nucleic Acids Res
Deutsch EW, Bandeira N, Perez-Riverol Y, Sharma V, Carver JJ, Mendoza L, Kundu DJ, Bandla C, Kamatchinathan S, Hewapathirana S, Sun Z, Kawano S, Okuda S, Connolly B, MacLean B, MacCoss MJ, Chen T, Zhu Y, Ishihama Y, Vizcaíno JA.   +19 more
europepmc   +1 more source

Growth Hormone‐Loaded 3D Printed Silk Fibroin‐Cellulose Dressings for Ischemic Wounds

Advanced Healthcare Materials, EarlyView.
3D‐printed wound dressings combining carboxymethyl cellulose, silk fibroin, and growth hormone accelerate healing in diabetic ulcers. These bioactive, customizable dressings enhance angiogenesis, cellular proliferation, and immune modulation. Proteomic analysis reveals activation of regenerative pathways and reduced fibrosis, highlighting their ...
Maria Pita‐Vilar, Diego Caicedo‐Valdés, Susana B. Bravo, Isabel Rodriguez‐Moldes, Salvador D. Aznar‐Cervantes, Angel Concheiro, Carmen Alvarez‐Lorenzo, Luis Diaz‐Gomez   +7 more
wiley   +1 more source

Mass Spectrometry Proteomics: A Key to Faster Drug Discovery. [PDF]

J Med Chem
Tagliazucchi L, Costi MP.
europepmc   +1 more source

Preliminary Study of a Ninj1‐Loaded Bimodal Ultrasound/NIR Fluorescence Targeted Molecular Probe for Diagnosing Early‐Stage Inflammation in Coronary Microvascular Dysfunction

Advanced Healthcare Materials, EarlyView.
Coronary microvascular dysfunction (CMD) targeting remains a challenge for precise diagnosis. This work presents a dual‐modal nanoprobe (T‐IR780‐NBs) that combines ultrasound contrast with near‐infrared fluorescence. This technology utilizes proteomics‐derived antibodies that specifically localize to inflamed and injured cardiac tissue, enabling ...
Xiaohui Xu, Lina Guan, Baihetiya Tayier, Chen Yuan, Shangke Chen, Qi Shi, Yuming Mu   +6 more
wiley   +1 more source

Proteomics research in aging: a bibliometric and visualized analysis of evolution and emerging trends (1998-2024 and early 2025). [PDF]

Biogerontology
Gao Y, Yang Y, Xue X, Xu Y, Yang J.
europepmc   +1 more source

Proteomic Analysis Reveals the Association between the Rho-GDI Signaling Pathway and Kidney Injury in Spontaneously Hypertensive and Hyperlipidemic Rats

, 2015
Yasuhiro Taki, Masayuki Oda, Anna S. Sedukhina, Atsuko Ikemori, Naoki Matsumoto, Yugo Shibagaki, Toshio Kumai   +6 more
openalex   +2 more sources

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems

Advanced Healthcare Materials, EarlyView.
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu, Ruiqi Wu, Hai Jiang, Lian Chen, Yingying Tian, Shuai Zeng, Tongmin Liu, Cheng Zhao, Huifeng Shi, Xiaolong Liang, Yangyu Zhao   +10 more
wiley   +1 more source

Correction: Unveiling the protein landscape for early detection of colorectal precancerous lesions. [PDF]

Clin Proteomics
Luo Y, Xiao C, Zheng C, Luo S, Jiang Y, You F, Fu X, Li X.   +7 more
europepmc   +1 more source