Results 41 to 50 of about 15,137,040 (190)

STANDARDIZATION OF PROTHROMBIN TIME TEST AND EVALUATION OF QUALITY OF PATIENT MANAGEMENT WITH WARFARIN

open access: yesJournal of Research in Medical Sciences, 2000
Background. The most common mode of monitoring anticoagulation therapy is the use of prothrombin time (PT). There exist several methods for reporting results of PT. These include prothrombin time in seconds, prothrombin activity percent, prothrombin time
A.H ZARGARZADEH, A.A POURAZAR, M MORABI
doaj  

The Determinant of the Prothrombin Time in Normal Human Plasma

open access: yes, 1958
SummaryNormal adult human plasma has a constant prothrombin time when determined under standardized conditions and with carefully prepared reagents. An explanation for this constancy is offered; namely, that a plasma factor, designated as “prothrombin ...
Armand J. Quick
core   +1 more source

Pharmacokinetics and efficacy of oral versus intravenous mixed-micellar phylloquinone (vitamin K-1) in severe acute liver disease [PDF]

open access: yes, 2005
Background/Aims: In patients with severe acute liver dysfunction, i.v. phylloquinone (vitamin K-1) may be given to exclude vitamin K deficiency, rather than impaired hepatic synthesis of coagulation factors alone, as the cause of the coagulopathy ...
Pereira, SP   +13 more
core   +1 more source

Quick or Owren prothrombin time methods: possibilities and limitations (literature review)

open access: yesМедицина неотложных состояний
Background. To treat patients with hypocoagulation, an objective assessment of the hemostasis system is mandatory. Owren prothrombin time method is rare in Ukrainian hospitals.
R.A. Zatsarynnyi   +4 more
doaj   +1 more source

Effects of Verapamil and Diltiazem on the Pharmacokinetics and Pharmacodynamics of Rivaroxaban

open access: yesPharmaceutics, 2019
Concomitant use of rivaroxaban with non-dihydropyridine calcium channel blockers (non-DHPs) might lead to an increase of systemic rivaroxaban exposure and anticoagulant effects in relation to the inhibition of metabolic enzymes and/or transporters by non-
Minsoo Kim   +5 more
doaj   +1 more source

Improvements of the method for the preparation of an artificial prothrombin reagent [PDF]

open access: yes, 1978
Improvements of a method to prepare a [bovine] prothrombin-free reagent for the 1-stage determination of prothrombin were discussed.
Vermeer, C., Soute, B.A.M., Hemker, H.C.
core   +1 more source

The mediating role of inflammation in the association between coagulation parameters and diabetic kidney diseases in patients with type 2 diabetes mellitus: a muti-center cross-sectional retrospective study in Southwest China from 2013 to 2022

open access: yesBMC Nephrology
Purpose This study aims to investigate the association between coagulation parameters and diabetic kidney diseases (DKD) with a specific focus on evaluating the potential mediating effects of inflammation.
Bei-Hui Ren   +7 more
doaj   +1 more source

CHALLENGES AND POSSIBLE SOLUTIONS IN DETERMINING INR

open access: yesАтеротромбоз, 2015
Despite the development of new oral anticoagulants, vitamin K antagonists (VKA) continue to be widely used for the treatment and prevention of throm-boembolic complications.
E. V. Titaeva, A. B. Dobrovolsky
doaj   +1 more source

Diagnostic utility of hematological and biochemical markers for cystic echinococcosis in Tibetan patients of Sichuan, China

open access: yesFrontiers in Cellular and Infection Microbiology
ObjectiveThis hospital-based case-control study aims to evaluate hematological and biochemical markers for the diagnosis of cystic echinococcosis (CE) in the Tibetan population of Sichuan.MethodsThis study involved 83 patients diagnosed with CE and 45 ...
Meng Ma   +4 more
doaj   +1 more source

Warfarin anticoagulation exacerbates the risk of hemorrhagic transformation after rt-PA treatment in experimental stroke: therapeutic potential of PCC [PDF]

open access: yes, 2011
Background: Oral anticoagulant therapy (OAT) with warfarin is the standard of stroke prevention in patients with atrial fibrillation. Approximately 30% of patients with cardioembolic strokes are on OAT at the time of symptom onset.
Förch, Christian   +14 more
core   +2 more sources

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