Results 1 to 10 of about 38,756 (241)
Expression of the mouse and rat mas proto‐oncogene in the brain and peripheral tissues [PDF]
FEBS Letters, 1995 We isolated the mas proto‐oncogene from a mouse genomic library. Sequence analysis showed that it contains an open reading frame without intervening sequences. The amino acid sequence deduced confirms the seven‐transmembrane‐domain structure and exhibits 97% and 91% amino acid homology with the rat and the human Mas, respectively. In mice and rats, mas
Metzger, Rainer +5 more
openaire +4 more sources
Up-regulation of the Angiotensin II Type 1 Receptor by the MAS Proto-oncogene Is Due to Constitutive Activation of Gq/G11 by MAS [PDF]
Journal of Biological Chemistry, 2006 Coexpression of the MAS proto-oncogene with the angiotensin II type 1 (AT(1)) receptor in CHO-K1 cells has been reported to increase the number of [(3)H]angiotensin II-binding sites, although MAS does not bind [(3)H]angiotensin II. In HEK293 cells stably expressing AT(1) receptor-cyan fluorescent protein (CFP), MAS-yellow fluorescent protein (YFP ...
Meritxell, Canals +3 more
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Cell Type-specific Expression of the Mas Proto-oncogene in Testis [PDF]
Journal of Histochemistry & Cytochemistry, 2002 The Mas proto-oncogene encodes a G-protein-coupled receptor with the common seven transmembrane domains and may be involved in the actions of angiotensins. Because Mas is highly expressed in testis, we investigated the cell type-specificity and the onset of expression of the gene in this organ.
Natalia, Alenina +6 more
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Angiotensin 1-7 Modulates the Dynamics and Activation of the Proto-oncogene Mas Receptor [PDF]
ABSTRACT The proto-oncogene Mas receptor (MasR, UniProt ID: P04201) is a class-A (orphan-type) G protein-coupled receptor (GPCR) that mediates the protective effects of Angiotensin 1-7 (Ang 1-7) within the renin–angiotensin system (RAS). Despite its therapeutic relevance, the molecular mechanisms underlying MasR activation by Ang 1-7 remain
Ekrem Yasar +3 more
openaire +2 more sources
Genomics, 1992 The mouse homolog of the human proto-oncogene MAS was mapped by two interspecific backcrosses to the proximal portion of MMU17. Higher resolution mapping was accomplished through the analysis of genotypes duplicated or deleted for a megabase-size subregion within MMU17.
J A, Cebra-Thomas +5 more
openaire +3 more sources
Cells, 2022 Gliomas are the most common primary brain tumors in adults. Significant progress has been made in recent years in identifying the molecular alterations involved in gliomas.
Florestan Courant +8 more
doaj +1 more source
LINFOMA DE ZONA MARGINAL (MALT) EM GLÂNDULA LACRIMAL - UM RELATO DE CASO
Hematology, Transfusion and Cell Therapy, 2023 Objetivos: O propósito deste estudo é divulgar os conhecimentos sobre um caso raro de linfoma de zona marginal (MALT) em glândula lacrimal, visando ampliar o conhecimento sobre essa doença no meio científico.
PC Gontijo +6 more
doaj +1 more source
Hematology, Transfusion and Cell Therapy, 2023 Objetivos: As neoplasias mieloides são resultantes de alterações moleculares na célula-tronco hematopoiética, sendo a leucemia mieloide aguda (LMA) a mais agressiva e com piores desfechos clínicos.
MFL Carvalho +7 more
doaj +1 more source
TheMASProto-Oncogene Is Not Imprinted in Humans [PDF]
Genomics, 1996 Recently it was shown that the murine Mas gene, which is located less than 300 kb from the imprinted Igf2r gene, is also imprinted in Day 11.5 embryos with expression exclusively from the paternal allele. We have assigned the human MAS gene to chromosomal bands 6q25.3-q26 in close proximity to the IGF2R gene.
Riesewijk, A. +4 more
openaire +4 more sources