Results 21 to 30 of about 8,187 (229)

Biological roles of mas oncogene. [PDF]

, 2002
Tsang Sup-Yin.Thesis (M.Phil.)--Chinese University of Hong Kong, 2002.Includes bibliographical references (leaves 176-185).Abstracts in English and Chinese.Acknowledgments --- p.1Abstract --- p.2摘要 --- p.4List of Abbreviation --- p.6Chapter Chapter 1

core  

Characterization of the rat mas oncogene and its high-level expression in the hippocampus and cerebral cortex of rat brain

, 1988
The human mas oncogene was originally detected by its ability to transform NIH 3T3 cells. We previously showed that the protein encoded by this gene is unique among cellular oncogene products in that it has seven hydrophobic potential transmembrane ...
Wigler, M. H., Jessell, T., Young, D., O'Neill, K.   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Neoplasia endocrina múltiple tipo-2B

Revista de la Facultad de Medicina, 2004
La neoplasia endocrina multiple tipo 2 comprende tres sindromes : la neoplasia endocrina múltiple 2A con predisposición genética para desarrollar carcinoma medular del tiroides, feocromocitoma e hiperplasia primaria de paratiroides.
Guido Lastra, Roberto Franco, Pedro Nel Rueda P., Lina P. Pradilla S., Óscar Paz C.   +4 more
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Role of Mas oncogene on angiotensin receptor expression. [PDF]

, 1999
Tang Wai-man.Thesis (M.Phil.)--Chinese University of Hong Kong, 1999.Includes bibliographical references (leaves 142-147).Abstract also in Chinese.Abstract --- p.i摘要 --- p.iiiAcknowledgement --- p.vLists of Abbreviations --- p.viTable of Contents ---

core  

Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains

, 1986
We have cloned and sequenced a new human oncogene and have named it mas. This oncogene was detected by its tumorigenicity in nude mice using the cotransfection and tumorigenicity assay previously described.
Wigler, M. H., Waitches, G., Young, D., Fasano, O., Birchmeier, C.   +4 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Effects of angiotensin II on proximal tubular cells stably transfected with the c-mas oncogene

, 1992
Angiotensin II (ANG II) normally induces cellular hypertrophy in proximal tubular epithelium by engaging receptor systems that use a G-protein-signaling mechanism. The c-mas oncogene also encodes part of a superfamily of vasoactive peptide receptor-like
E. G. Neilson, G. Wolf
core   +1 more source

Angiotensin 1-7 Modulates the Dynamics and Activation of the Proto-oncogene Mas Receptor

Journal of Molecular Recognition
ABSTRACT The proto-oncogene Mas receptor (MasR, UniProt ID: P04201) is a class-A (orphan-type) G protein-coupled receptor (GPCR) that mediates the protective effects of Angiotensin 1-7 (Ang 1-7) within the renin–angiotensin system (RAS).
Ekrem Yasar, Segun Dogru, Erol Eroglu, Nazmi Yaras   +3 more
openaire   +1 more source