Results 11 to 20 of about 1,121,649 (218)
The proto-oncogene serine/threonine-protein kinase PIM3 plays critical roles in cancer, and it has been extensively exploited as a drug target. Here, we investigated the quantitative changes in the cellular proteome and phosphoproteome in liver cancer ...
Yan Gao (93649) +8 more
core +5 more sources
O PROTO-ONCOGENE RAS NO BÓCIO MULTINODULAR [PDF]
Neoplastic transformation results from a series of genetic alterations involving activation of protooncogenes and inactivation of tumor suppressor genes.
Lobato, Rafael +5 more
core +2 more sources
The role of the proto-oncogene Ski in cortical development [PDF]
The proto-oncogene Ski is an evolutionary conserved protein associated with various cellular processes such as proliferation and differentiation as well as transformation and tumor progression.
Baranek, Constanze Katharina Charlotte
core +1 more source
Murine c-erbB2: an oncogene that could be a target for vaccination therapy? : and the effect of HER2/c-erbB2/NeuT expression on cell signaling and milk protein formation in mouse mammary epithelial cells [PDF]
ErbB2 is an orphan receptor tyrosine kinase which can dimerize with other ligand-activated members of the EGF receptor family to signal in pathways inducing cell proliferation. Frequently overexpressed in breast cancer and other human cancers, homologs
Noyer, Mathieu
core +1 more source
JUNB (jun B proto-oncogene) [PDF]
Review on JUNB (jun B proto-oncogene), with data on DNA, on the protein encoded, and where the gene is ...
Chen, F
core +1 more source
MERTK (c-mer proto-oncogene tyrosine kinase) [PDF]
Review on MERTK (c-mer proto-oncogene tyrosine kinase), with data on DNA, on the protein encoded, and where the gene is ...
Keating, AK, Linger, RMA, Graham, DK
core +1 more source
Proto-oncogene c-jun expression is induced by AML1-ETO in a JNK dependent manner:possible role in the pathogenesis of acute myeloid leukemia [PDF]
Overexpression of proto-oncogene c-jun and constitutive activation of the Jun NH2-terminal kinase (JNK) signaling pathway have been implicated in the leukemic transformation process.
Elsaesser, Annika
core +1 more source
RET proto-oncogene and thyroid cancer [PDF]
TheRET proto-oncogene has not only conclusively been identified as responsible for the three subtypes of the inherited cancer syndrome multiple endocrine neoplasia type 2 (MEN-2) but also shown to be involved in the molecular evolution of sporadic ...
Komminoth, Paul
core +1 more source
Background: Cardiac aging is associated with myocardial remodeling and reduced angiogenesis. Counteracting these changes with natural products is a preventive strategy with great potential.
Elena Daskalova +7 more
doaj +1 more source
Neoplasias endocrinas múltiples: de lo molecular a lo clínico
Resumen: Las neoplasias endocrinas múltiples (NEM) tipo 1, 2 (se subdivide en 2A y 2B), 4 y 5; constituyen síndromes genéticos hereditarios con un patrón de transmisión autosómico dominante.
Nelson Wohllk, MD, Consuelo Olave, MD
doaj +1 more source

