Results 151 to 160 of about 440,834 (358)

Proto-oncogene Protein Sequence Classification using RNN and CNN with Attention Mechanism

, 2023
Et al. M.Vijayalakshmia
openalex   +2 more sources

Response : Sperm-Egg Binding Protein or Proto-Oncogene? [PDF]

Science, 1996
P, Saling, R, Carballada, D, Burks, H, Moore   +3 more
openaire   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

COMPUTERIZED PROTEIN MODELING AND MOLECULAR DOCKING ANALYSIS OF HUMAN PROTO ONCOGENE TYROSINE PROTEIN KINASE YES FOR DISCOVERY OF NOVEL LEAD MOLECULES [PDF]

, 2010
Amineni Umamaheswari, Karuna Jaya Sai, Dibyabhaba Pradhan, Amineni Umamaheswari   +3 more
openalex   +1 more source

Increased expression of YAP1 in prostate cancer correlates with extraprostatic extension. [PDF]

, 2017
Objective:Yes associated protein 1 (YAP1) is a member of the Hippo pathway, acting as a transcriptional coactivator. To elucidate the role of YAP1 and phosphorylated (p)YAP1 in prostate cancer (PCa) tumorigenesis, we investigated their expression in ...
Collak, Filiz Kisaayak, Demir, Ummuhan, Kurum, Esra, Ozkanli, Seyma, Zerk, Pinar Engin   +4 more
core  

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Src-homology domain 2 containing protein tyrosine phosphatase-1 (SHP-1) directly binds to proto-oncogene tyrosine-protein kinase Src (c-Src) and promotes the transcriptional activation of connexin 43 (Cx43) [PDF]

, 2022
Yihao Liu, Meng Dai, Penghui Yang, Cao Li, Lu Li   +4 more
openalex   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

BRAF V600E Mutation in Odontogenic Keratocyst: A Systematic Review and Meta-Analysis

Pesquisa Brasileira em Odontopediatria e Clínica Integrada
Objective: To assess the frequency of the BRAF V600E mutation in odontogenic keratocyst, correlating the methods of evaluation and detection of the mutated protein.
Jéssica da Silva Cunha, Lucas Nascimento Ribeiro, Allan Vinícius Martins-de-Barros, Raisa Jordana Geraldine Severino-Lazo, Raíssa Soares dos Anjos, Renata de Albuquerque Cavalcanti Almeida, Mohammed N. Islam, Marianne de Vasconcelos Carvalho   +7 more
doaj  

Expression and Significance of COX-2 and its Transcription Factors NFAT3 and c-Jun in Non-small Cell Lung Cancer

Chinese Journal of Lung Cancer, 2010
Background and objective Cyclooxygenases (COX), the key enzymes in the conversion of arachidonic acid (AA) to prostaglandins (PGs), are involved in initiation and progression of cancer.
Xiaohong ZHAO, Zhaoli CHEN, Shouhua ZHA, Jie HE   +3 more
doaj   +1 more source