Results 251 to 260 of about 440,834 (358)

Oncogenic B-Raf proto-oncogene, serine/threonine kinase-mediated hedgehog signalling in the pathogenesis and targeted therapy of melanoma. [PDF]

World J Clin Oncol
Rather RA.
europepmc   +1 more source

Activation of the Erk8 Mitogen-activated Protein (MAP) Kinase by RET/PTC3, a Constitutively Active Form of the RET Proto-oncogene [PDF]

, 2006
Carlo Iavarone, Mario Acunzo, Francesca Carlomagno, Annunziata Catania, Rosa Marina Melillo, Stella M. Carlomagno, Massimo Santoro, M Chiariello   +7 more
openalex   +1 more source

A20 Facilitates Oxaliplatin Sensitivity in Colorectal Cancer Through Monoubiquitylation of IKK‐β

Advanced Science, EarlyView.
This study demonstrates that the expression of A20, a ubiquitin‐editing enzyme, is positively correlated with oxaliplatin sensitivity in colorectal cancer (CRC). Mechanistically, A20 enhances oxaliplatin sensitivity by inhibiting NF‐κB nuclear translocation through monoubiquitination of IKK‐β.
Fan Luo, Ting Yang, Jiaxin Cao, Qun Chen, Zhenhai Lu, Feiteng Lu, Chaozhuo Lin, Zengfei Xia, Yuanzhong Yang, Peng Li, Wenjuan Ma, Min Luo, Rongxin Zhang   +12 more
wiley   +1 more source

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion. [PDF]

Int J Oncol
Gao J, Mcconnell MJ, Yu B, Li J, Balko JM, Black EP, Johnson JO, Lloyd MC, Altiok S, Haura EB.   +9 more
europepmc   +1 more source

Differentiation of the mononuclear phagocyte system during mouse embryogenesis:the role of transcription factor PU.1 [PDF]

, 1999
Browne, C M, Henkel, G W, Hume, D A, Lichanska, A M, Maki, R A, McKercher, S R, Murphy, K M, Ostrowski, M C   +7 more
core  

Logic‐Gated HSV‐TK/GCV Suicide Gene Circuit for Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
The BRAS comprises two modular genetic components driven by distinct tumor‐specific promoters and a failsafe layer with the NOT gate. This multi‐input logic gate circuit enables precise, specific expression of HSV‐TK in breast cancer cells with hardly expression in normal cell and effectively inhibits tumor growth in a triple‐negative breast cancer ...
Shasha Tang, Yuan Fang, Lingli Jin, Dongyang Liu, Yicheng Liu, Ruijia Zheng, Liyun Yong, Xin Wu, Longliang Qiao, Meiyan Wang, Fengfeng Cai   +10 more
wiley   +1 more source

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells. [PDF]

Oncol Rep
Zhu D, Wan X, Huang H, Chen X, Liang W, Zhao F, Lin T, Han J, Xie W.   +8 more
europepmc   +1 more source

Two-edged sword: how activation of the “proto-oncogene” yes-associated protein 1 in lung squamous cell carcinoma can surprisingly inhibit tumor growth [PDF]

, 2018
Thomas Andl, Claudia D. Andl, Yuhang Zhang   +2 more
openalex   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Study on the correlation between Interleukin 4 and febrile seizures. [PDF]

Cytojournal
Xiang X, Wang S, Tang C, Jin H, Lei L, Mao G, Huang X, Huang B.   +7 more
europepmc   +1 more source