Results 31 to 40 of about 197,127 (261)
RAS proto-oncogene in medullary thyroid carcinoma.
Endocrine-Related Cancer, 2015 Medullary thyroid carcinoma (MTC) is a rare malignancy originating from the calcitonin-secreting parafollicular thyroid C cells. Approximately 75% of cases are sporadic.
M. Moura, B. Cavaco, V. Leite
semanticscholar +1 more source
Expression and Function of the c-kit Proto-Oncogene Protein in Mouse Sperm1 [PDF]
Biology of Reproduction, 1997 The presence and role of the c-kit protein were examined in mature sperm of the mouse. Monoclonal antibodies (mAbs) against the c-kit protein were used to perform immunohistochemical staining, electron microscopy studies, and Western blot analysis. The acrosomal region of both fixed and unfixed noncapacitated sperm stained with the antibodies.
Huailiang Feng +2 more
openaire +3 more sources
Binding of anisotropic curvature-inducing proteins onto membrane tubes [PDF]
Soft Matter 18, 3384-3394 (2022), 2022 Bin/Amphiphysin/Rvs superfamily proteins and other curvature-inducing proteins have anisotropic shapes and anisotropically bend biomembrane. Here, we report how the anisotropic proteins bind the membrane tube and are orientationally ordered using mean-field theory including an orientation-dependent excluded volume.
arxiv +1 more source
Identification of Protein Products Encoded by the Proto-Oncogene int-1 [PDF]
Molecular and Cellular Biology, 1987 The proto-oncogene int-1 is activated by adjacent insertions of proviral DNA in mouse mammary tumor virus-induced tumors and has transforming activity in certain mammary epithelial cell lines. The gene is normally expressed in the central nervous system of mid-gestational embryos and in the adult testis.
Harold E. Varmus +4 more
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Metanephric Adenoma with cystic changes- An uncommon presentation of a rare tumor in a young adult
Autopsy and Case Reports, 2021 Metanephric adenoma (MA) is a rare benign neoplasm of the kidney that is usually asymptomatic and incidentally diagnosed. MA usually present as a solid mass; however, a cystic presentation has been reported.
Darilin Shangpliang +6 more
doaj
Archives of Pharmaceutical Sciences Ain Shams University, 2021 Transcription factors (TFs) as SRY-Box transcription factor 11 (SOX11) and B-cell lymphoma/leukemia 11A (BCL11A) role in breast cancer (BC) as well as their effect on epithelial cadherin (E-cadherin) membrane protein which is a metastasis suppressor is a
Salma Salama +3 more
doaj +1 more source
Curvature sensing of curvature-inducing proteins with internal structure [PDF]
Phys. Rev. E 109, 024403 (2024), 2023 Many types of peripheral and transmembrane proteins can sense and generate membrane curvature. Laterally isotropic proteins and crescent proteins with twofold rotational symmetry, such as Bin/Amphiphysin/Rvs superfamily proteins, have been studied theoretically. However, proteins often have an asymmetric structure or a higher rotational symmetry.
arxiv +1 more source
Genes & Development, 1996 The paired box transcription factor Pax-5 (B-cell-specific activator protein) is a key regulator of lineage-specific gene expression and differentiation in B-lymphocytes.
D. Fitzsimmons +5 more
semanticscholar +1 more source
Effects of Antibiotics and a Proto-Oncogene Homolog on Destruction of Protein Translocator SecY [PDF]
Science, 2009 Jamming Protein Translocation Antibiotics are tremendously important drugs in modern medicine, yet we are still learning precisely how they work. SecY is a bacterial membrane protein that is part of a complex that allows protein secretion across the membrane. Van Stelten et al.
van Stelten, Johna +3 more
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Autopsy and Case Reports, 2017 BRAF protein is a serine/threonine kinase with 766 amino acids. Approximately 15% of human cancers harbor BRAF mutations as well as other BRAF anomalies (amplifications, fusions).
Amir Ghorbani-Aghbolaghia +5 more
doaj +1 more source