Results 21 to 30 of about 13,736,509 (195)
Risk factors analysis for BRAF gene V600E mutation in patients with infiltrative follicular papillary thyroid carcinoma [PDF]
精准医学杂志Objective To investigate the risk factors for BRAF gene V600E mutation in patients with infiltrative follicular papillary thyroid carcinoma (IF-PTC). Methods A total of 134 patients with IF-PTC who underwent surgical treatment in our hospital from August
LI Lei, ZHAN Jiezhi, LI Hui, WANG Ruiqing, ZHAO Cheng
doaj +1 more source
Guilty as charged B-RAF is a human oncogene [PDF]
, 2004 RAF proteins are components of a conserved signaling pathway that regulates cellular responses to extracellular signals. Despite over 20 years of research into the regulation and function of the RAF proteins, it was only realized recently that the B-RAF ...
Marais, Richard, Garnett, Mathew J.
core +1 more source
Mechanism of regulation of Raf-1 by Ca2+/Calmodulin-dependent kinase II [PDF]
, 2011 The calcium-calmodulin dependent kinase II (CaMKII) is an ubiquitous serine/threonine protein kinase involved in multiple signalings and biological functions.
Salzano, Marcella
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World Journal of Surgical Oncology, 2023 Background Microcalcifications are suggested to be an indicator of thyroid malignancy, especially for papillary thyroid carcinoma (PTC), nonetheless, the association between macrocalcification and PTC is underexplored. Furthermore, screening methods like
Mengyao Ye +6 more
doaj +1 more source
Exploration of Targeted Anti-tumor Therapy, 2022 Multiple myeloma (MM) is a blood cancer that derives from plasma cells (PCs), which will accumulate in the bone marrow (BM). Over time, several drugs have been developed to treat this disease that is still uncurable.
Vincenzo Raimondi +5 more
doaj +1 more source
Journal of Medical Case Reports, 2017 Background Histiocytic sarcoma is a rare histiocytic neoplasm of unknown etiology that constitutes less than 1% of hematologic malignancies. A few cases of histiocytic sarcoma harboring the BRAF V600E mutation have been reported, but this finding has not
John L. Vaughn +3 more
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JUNB (jun B proto-oncogene) [PDF]
, 2003 Review on JUNB (jun B proto-oncogene), with data on DNA, on the protein encoded, and where the gene is ...
Chen, F
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Current concepts in ameloblastoma-targeted therapies in B-raf proto-oncogene serine/threonine kinase V600E mutation: Systematic review [PDF]
, 2020 Ameloblastomas are common benign epithelial odontogenic neoplasms that present an aggressive and unpredictable behavior that may modify treatment strategies.
Carreón Burciaga, Ramón Gil +6 more
core +1 more source
Immune check point inhibitors in BRAF mutated metastatic colorectal cancer: A review
International Journal of Gastrointestinal InterventionMetastatic colorectal cancers with BRAF mutation are a class of tumors that have a poor prognosis compared to wild type patients. Even if this group has found some hope in targeted therapy with multi-targeted blockade of the mitogen-activated protein ...
Alfredo Colombo +2 more
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BRAF inhibitor or BRAF/MEK inhibitor treatment for patients with metastatic BRAF V600E mutated differentiated thyroid cancer [PDF]
Archives of Endocrinology and MetabolismObjective: The aim of this study is to demonstrate the real-life efficacy of BRAF and MEK inhibitors in patients with advanced thyroid cancer. Subjects and methods: This retrospective study evaluated the clinical efficacy of either a BRAF inhibitor ...
Inbar Finkel +9 more
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