Results 111 to 120 of about 40,019,280 (182)

Magnetic Nanomedicine for Cancer: Mechanisms, Modalities, and Translation

Nano Select, Volume 7, Issue 9, September 2026.
At the convergence of nanotechnology, precision oncology and intelligent therapeutics, magnetic nanoparticles (MNPs) are redefining how cancer is detected, targeted and treated. This review critically examines the mechanisms enabling their integration in imaging, targeted drug delivery and magnetic hyperthermia, while exploring how intelligent design ...
Shivani Kadam, Rahul M. Sonavale, Ratnesh Das, Jayant Pawar, Nutan Shukla, Zhengyou Li, Girish R. Pathade, Nishabh Kushwaha, Asha Patel, Sushilkumar A. Jadhav, Samuel B. Adeloju   +10 more
wiley   +1 more source

Case Report: Long-term survival of refractory high-grade B-cell lymphoma with MYC, BCL2, and BCL6 rearrangements through glofitamab monotherapy consolidated by ASCT. [PDF]

Front Immunol
Fang F, Ni J, Zhao H, Hui W, Sun X, Zou D, Sun W.   +6 more
europepmc   +1 more source

Comprehensive Chemical and Biological Assessment of Orobanche racemosa Extracts Using Chromatographic, In Vitro, In Silico, and Cell‐Based Techniques

ChemistryOpen, Volume 15, Issue 9, September 2026.
Orobanche racemosa can be considered an effective source of natural bioactive agents in designing functional applications. The growing interest in natural product research as a safer and sustainable alternative to synthetic drugs has triggered this study, which evaluates the chemical profile and biological activity of Orobanche racemosa extracts.
Nilofar Nilofar, Enver Saka, Mehmet Veysi Cetiz, Maria J. Rodrigues, Eliana Fernandes, Luisa Custodio, Evren Yildiztugay, Ismail Yapıcı, Ilhami Gulcin, Esraa A. Elhawary, Omayma A. Eldahshan, Abdel Nasser B. Singab, Carlos L. Cespedes‐Acuna, Gokhan Zengin   +13 more
wiley   +1 more source

Comment on AlAsmari et al. Venetoclax Induces Cardiotoxicity through Modulation of Oxidative-Stress-Mediated Cardiac Inflammation and Apoptosis via NF-κB and BCL-2 Pathway. <i>Int. J. Mol. Sci.</i> 2022, <i>23</i>, 6260. [PDF]

Int J Mol Sci
Trela BA, Guffroy MR.
europepmc   +1 more source

Histiocytosis development and clinical variation through the lens of genomics

The Journal of Pathology, Volume 270, Issue 1, Page 23-39, September 2026.
Abstract Histiocytic neoplasms are rare haematologic diseases characterised by clonal expansions of cells with a monocyte, macrophage or dendritic cell phenotype. Their clinical manifestations are diverse, ranging from indolent lesions to aggressive systemic disease.
Paul G Kemps, Astrid GS van Halteren, Tom van Wezel, Pancras CW Hogendoorn   +3 more
wiley   +1 more source

Evaluation of the anti-apoptotic, anti-platelet aggregation, and pro-angiogenic properties of Naoshuantong capsule in ischemic stroke: insights from network pharmacology and animal experiments. [PDF]

J Tradit Chin Med
Chuanpeng LI, Yaoyao Y, Yingzhi XU, Ping J, Luda F, Ying G, Xinglu D.   +6 more
europepmc   +1 more source

Matrine Suppresses Lung Cancer Progression via Dual Inhibition of CHEK1‐Mediated DNA Damage Repair and PI3K/AKT Survival Signaling

Thoracic Cancer, Volume 17, Issue 18, September 2026.
Matrine simultaneously targets CHEK1 (impairing DNA repair, increasing γH2AX) and PI3K/AKT (activating mitochondrial apoptosis), reduced EMT, and strong in vitro and in vivo antitumor effects with low toxicity, positioning it as a promising dual‐mechanism agent for lung cancer.
Jianghao Yu, Siyang Chen, Tingting Hou, Xianwu Weng, Yakun Liu, Junchao Huang, Zeshan Yang, Jinyu Bao, Changshuai Zhou, Wanqing Lv, Qingzhe Wu, Yun Xu, Jinshan Zhou   +12 more
wiley   +1 more source

Resistance pathways and next-generation treatments in chronic lymphocytic leukemia. [PDF]

Discov Oncol
Bellemrrabet R, Rachid E, Lahmouad M, Aboussaleh Y, Al Abdulmonem W, Bouyahya A, Abboussi O, Amahdar L.   +7 more
europepmc   +1 more source

Hypericin Suppresses Liver Cancer Through Autophagic Degradation of AKT and Eliciting Antitumor Immune Response

Cancer Science, Volume 117, Issue 9, Page 2567-2585, September 2026.
Hypericin induces autophagic AKT degradation by promoting AKT‐HSPA5 interaction in an S473 phosphorylation‐dependent manner, suppressing HCC growth. It enhances CD8+ T cell‐mediated antitumor immunity and synergizes with anti‐PD‐L1 therapy, showing favorable safety for HCC treatment. ABSTRACT Hepatocellular carcinoma (HCC) is the most prevalent primary
Sien Ma, Qianqian Xu, Mengjuan Zhu, Xianming Ge, Jian Xu, Yan Pan, Mengli Wang, Yuting Zhu, Aoxuan Xu, Hanmeng Liu, GuangHai Xiang, Weipeng Gong, Bao Zhao   +12 more
wiley   +1 more source

[Expression of Concern] Dexmedetomidine protects against sepsis‑associated encephalopathy through Hsp90/AKT signaling. [PDF]

Mol Med Rep
Yin L, Chen X, Ji H, Gao S.
europepmc   +1 more source