Results 81 to 90 of about 82,943 (135)

Nucleic acid technology and infectious diseases [PDF]

, 1997
The past decade has witnessed an explosion in the knowledge of microbial genetics, pathogenesis, and antimicrobial resistance as a result of advances in molecular technology.
Luk, WK, Wong, SSY, Woo, PCY, Yuen, KY
core  

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, Volume 158, Issue 2, Page 382-408, 15 January 2026.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source

DNA methyltransferase inhibitors in hematological malignancies and solid tumors

International Journal of Cancer, Volume 158, Issue 2, Page 433-461, 15 January 2026.
Abstract Epigenetic modifications such as DNA methylation play a fundamental role in oncogenesis and the progression of neoplasms neoplasias. DNA methyltransferase inhibitors (DNMTi) constitute a family of therapeutic agents that impede the methylation at the 5‐position on cytosine nucleotides, thereby modulating the epigenetic regulation of tumor ...
Valentin Wenger, Guillermo Garcia‐Manero, Robert Zeiser, Michael Lübbert   +3 more
wiley   +1 more source

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion. [PDF]

Int J Oncol
Gao J, Mcconnell MJ, Yu B, Li J, Balko JM, Black EP, Johnson JO, Lloyd MC, Altiok S, Haura EB.   +9 more
europepmc   +1 more source

Study on the correlation between Interleukin 4 and febrile seizures. [PDF]

Cytojournal
Xiang X, Wang S, Tang C, Jin H, Lei L, Mao G, Huang X, Huang B.   +7 more
europepmc   +1 more source

A Computational Approach for the Prediction of p53 and BCL-2 Protein-Protein Interactions. [PDF]

Int J Mol Sci
Creamer C, Neely V, Harada H.
europepmc   +1 more source

Molecular Mechanism Discovery of Acacetin Against Cancers: Insights from Network Pharmacology and Molecular Docking. [PDF]

Int J Mol Sci
Jang JY, Kim D, Im E, Lee NK, Kim ND.
europepmc   +1 more source

IL-1β Controls Proliferation, Apoptosis, and Necroptosis Through the PI3K/AKT/Src/NF-κB Pathway in Leukaemic Lymphoblasts. [PDF]

Biomedicines
Victoria-Avila ZL, Reyes-Maldonado E, Domínguez-López ML, Vela-Ojeda J, Lozada-Ruiz A, Alemán OR, Lezama RA.   +6 more
europepmc   +1 more source

Network pharmacology analysis and experimental validation elucidate the protective mechanisms of BYHWD against hypoxia/reoxygenation-induced endothelial cell injury. [PDF]

Front Med (Lausanne)
Shi Y, Zhu Q, Zhou Y, Guan Q, Wen Q, Sun Y, Yan Z, Li Y, Zhao Y, Liu L, Lin H, Wang D.   +11 more
europepmc   +1 more source

Exploring the mechanism of Danggui Niantong Decoction in the treatment of rheumatoid arthritis based on network pharmacology, Mendelian randomization, molecular docking and molecular dynamics simulation. [PDF]

Medicine (Baltimore)
Wang H, Fan B, Liu M, Shu Q, Huang Y, Sun Q, Wang H.   +6 more
europepmc   +1 more source