Results 11 to 20 of about 34,683 (130)

Nuclear proto-oncogene products transactivate the human papillomavirus type 16 promoter. [PDF]

, 1995
Human papillomavirus (HPV) type 16 and 18 viral genomes are frequently detected in cervical and penile cancer biopsies. Although this strongly suggests a prominent role for HPV infection in the development of genital cancer, other genetic or ...
Artuc, M., Czarnetzki, B. M., Kalkbrenner, F., Moelling, K., Nürnberg, W., Schadendorf, D., Vorbrueggen, G.   +6 more
core   +2 more sources

Hexachlorobenzene-Induced Early Changes in Ornithine Decarboxylase and Protein Tyrosine Kinase Activities, Polyamines and c-Myc, c-Fos and c-Jun Proto-Oncogenes in Rat Liver [PDF]

Toxicological Sciences, 2003
El hexaclorobenceno (HCB) es un compuesto químico lipófilo que se distribuye ampliamente en el medio ambiente. Se sabe que el HCB causa tumores hepáticos en animales de experimentación. En el presente estudio se investigó el efecto in vivo del tratamiento con HCB sobre las actividades de la ornitina descarboxilasa (ODC) y la proteína tirosina quinasa ...
Andrea S, Randi, Susana, Hernandez, Laura, Alvarez, Marcela, Sanchez, Marta, Schwarcz, Diana L, Kleiman d Pisarev   +5 more
openaire   +2 more sources

Ras-mediated phosphorylation of a conserved threonine residue enhances the transactivation activities of c-Ets1 and c-Ets2 [PDF]

, 1996
The Ras oncogene products regulate the expression of genes in transformed cells, and members of the Ets family of transcription factors have been implicated in this process.
Colman, M S, Hauser, C A, Henkel, G, Hume, D A, Maki, R A, Ostrowski, M C, Stacey, K J, Van Beveren, C, Yang, B S   +8 more
core   +2 more sources

Transcriptomic and ChIP-sequence interrogation of EGFR signaling in HER2+ breast cancer cells reveals a dynamic chromatin landscape and S100 genes as targets. [PDF]

, 2019
BACKGROUND:The Human Epidermal Growth Factor Receptor (EGFR/HER1) can be activated by several ligands including Transforming Growth Factor alpha (TGF-α) and Epidermal Growth Factor (EGF).
Dutta, Pranabananda, Farias-Eisner, Robin, Nava, Miguel, Vadgama, Jaydutt V, Wu, Yanyuan, Zemke, Nathan R   +5 more
core   +5 more sources

Fracture healing induces expression of the proto‐oncogene c‐fos in vivo Possible involvement of the Fos protein in osteoblastic differentiation

FEBS Letters, 1991
Here we report marked in vivo expression of the c‐fos gene in the external soft callus (ESC) and periosteal hard callus (PHC) at the fracture site of adult rat tibia. Northern‐blot analysis showed that the ESC expressed a high level of c‐fos mRNA from post‐fracture day 10 to day 28, the time when endochondral ossification progressed, and that the ...
Ohta, Shuichi, Yamamuro, Takao, Lee, Kaechoong, Okumura, Hideo, Kasai, Ryuichi, Hiraki, Yuji, Ikeda, Toshihiko, Iwasaki, Rempei, Kikuchi, Haruki, Konishi, Junji, Shigeno, Chohei   +10 more
openaire   +2 more sources

Bone morphogenetic proteins (BMP‐2 and BMP‐3) induce the late phase expression of the proto‐oncogene c‐fos in murine osteoblastic MC3T3‐E1 cells [PDF]

FEBS Letters, 1992
Here we report that bone morphogenetic proteins 2 and 3 (BMP‐2 and BMP‐3) induced marked expression of c‐fos mRNA in a biphasic manner, i.e. the late phase (48 to 60 h) as well as the immediate‐early phase (0.5 h), in murine osteoblastic MC3T3‐El cells in vitro.
Ohta, Shuichi, Hiraki, Yuji, Shigeno, Chohei, Suzuki, Fujio, Kasai, Ryuichi, Ikeda, Toshihiko, Kohno, Hiroaki, Lee, Kaechoong, Kikuchi, Haruki, Konishi, Junji, Bentz, Hanne, Rosen, David M., Yamamuro, Takao   +12 more
openaire   +2 more sources

Gonadotropin and kisspeptin gene expression, but not GnRH, are impaired in cFOS deficient mice. [PDF]

, 2015
cFOS is a pleiotropic transcription factor, which binds to the AP1 site in the promoter of target genes. In the pituitary gonadotropes, cFOS mediates induction of FSHβ and GnRH receptor genes.
Coss, Djurdjica, Jonak, Carrie R, Kauffman, Alexander S, Xie, Changchuan   +3 more
core   +1 more source

The deazaguanine‐derivative, queuine, affects cell proliferation, protein phosphorylation and the expression of the proto oncogenes c‐fos and c‐myc in HeLa cells [PDF]

FEBS Letters, 1990
In higher eukaryotes the hypermodified guanine analogue, queuine (7‐(5‐(((1S,4S,5R)‐4,5‐dihydroxy‐2‐cyclopentene‐1‐yl)amino)‐methyl)‐7‐deazaguanine), occurs free or as modified nucleoside (Q) in the anticodon of specific tRNAs. Fast proliferating tissues and tumors contain considerable amounts of free queuine and Q‐deficient tRNAs.
Langgut, W., Kersten, H.
openaire   +2 more sources

Rapamycin-induced inhibition of HTLV-I LTR activity is rescued by c-Myb. [PDF]

, 2007
BACKGROUND: Rapamycin is an immunosuppressive which represses translation of transcripts harbouring a polypyrimidine motif downstream of the mRNA cap site through the mammalian target of rapamycin complex.
Lever, Andrew ML, Rose, Nicola J
core   +4 more sources

Complex-based analysis of dysregulated cellular processes in cancer [PDF]

, 2014
Background: Differential expression analysis of (individual) genes is often used to study their roles in diseases. However, diseases such as cancer are a result of the combined effect of multiple genes.
Khanna, Kum Kum, Liu, Chao, Madhamshettiwar, Piyush B., Ragan, Mark A., Simpson, Peter T., Song, Sarah, Srihari, Sriganesh   +6 more
core   +1 more source