Results 31 to 40 of about 19,964,650 (157)

High Levels of c-fos Proto-Oncogene Expression in Normal Human Adult Skin [PDF]

, 1990
The proto-oncogene c-fos is thought to play an important role in the modulation of cell growth and differentiation. In normal tissues that have been studied to date, c-fos expression has been found to be regulated in a tissue-specific manner.
Basset-Séguin, Nicole, Mion, Henri, Blanchard, Jean Marie, Kerai, Cecile, Verrier, Bernard, Escot, Chantal, Guilhou, Jean Jacques   +6 more
core   +1 more source

Expression and Significance of COX-2 and its Transcription Factors NFAT3 and c-Jun in Non-small Cell Lung Cancer

Chinese Journal of Lung Cancer, 2010
Background and objective Cyclooxygenases (COX), the key enzymes in the conversion of arachidonic acid (AA) to prostaglandins (PGs), are involved in initiation and progression of cancer.
Xiaohong ZHAO, Zhaoli CHEN, Shouhua ZHA, Jie HE   +3 more
doaj   +1 more source

The expression and significance of proto-oncogene c-fos in viral myocarditis [PDF]

, 2010
Background c-fos may play a role in the pathogenesis of some diseases. The expression and function of c-fos in viral myocarditis (VMC) have not yet been reported.
Zhang Song, He Ben, Ge Junbo, Wang Zuyue, Ruiz George, Goldstein Steven   +5 more
core   +2 more sources

A biologia molecular no prognóstico do carcinoma da tireóide

Revista do Colégio Brasileiro de Cirurgiões
This overview examines some selected genetic mechanisms of cancer development. Strong evidence has been accumulated suggesting that alteration in either the struture or activity of proto-oncogene contributes to the development and for the maintenance of ...
Aluizio Soares de Souza Rodrigues
doaj   +1 more source

C-fos proto-oncogene transient transcription is negatively affected in the Ela4-2 transformed rat cell line

, 1993
To study the effects of the regulatory phosphoprotein ICP4 of the Herpes simplex virus, (HSV), a DNA tumor virus, on the induction of gene expression by the epidermal growth factor (EGF), we have constructed a cell line, ELa4-2, which constitutively ...
C. Bovolenta, LIBOI E., ROMANELLI MG, E. M. Cattozzo, LIBOI, Elio Maria, M. Tognon, TOGNON, Mauro, ROMANELLI, Maria, BOVOLENTA C, CATTOZZO E. M   +9 more
core   +2 more sources

Dynamic Loading Regulates Meniscus‐Like Matrix Production in Human Mesenchymal Stromal Cell‐Seeded PET Scaffolds

Advanced Healthcare Materials, EarlyView.
Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira, Luisa de Roy, Anna‐Lotta Feldmeier, Mubashir Ahmad, Sofia Pilão, Maria Ahrens, Anita Ignatius, Carsten Linti, Andreas Martin Seitz   +8 more
wiley   +1 more source

Cloning, structural organization, and chromosomal assignment of the porcine c-fos proto-oncogene, FOS

, 2000
The complete porcine c-fos proto-oncogene (FOS) with flanking regions was cloned and sequenced. FOS consists of four exons at amino acids 1-47, 48-131, 132-167, and 168-380 and includes all the typical motifs of the fos proto-oncogene.
Brenig, Bertram, Geldermann, H., Reiner, Johannes R., Heinricy, L., Dzapo, V.   +4 more
core   +1 more source

Ovarian Cancer Diagnosis and Chemoresistance Prediction Model Based on cfRNA Molecular Signature

Advanced Science, EarlyView.
A deep learning model analyzes cfRNA profiles extracted from the blood of OVCA patients. This innovative approach distinguishes OVCA from healthy controls with high accuracy. Crucially, it reliably predicts patient response to chemotherapy (sensitive versus resistant subgroups).
Qinhao Guo, Yangyang Zhang, Yongcheng Jin, Siwei Deng, Yongqi Chen, Zheng Feng, Hao Wen, Liu Wang, Yilin Li, Fanghong Ou, Yong Shen, Haiming Li, Tianyao Zhou, Xingzhu Ju, Xiaohua Wu   +14 more
wiley   +1 more source

Hypomethylation of GNA15 Promotes Pancreatic Ductal Adenocarcinoma Progression and Macrophage M2 Polarization via STAT3‐CXCL8 Axis

Advanced Science, EarlyView.
A schematic model summarizing GNA15's mechanism in mediating macrophage M2 polarization and Gemcitabine resistance. ABSTRACT The complexity of pancreatic ductal adenocarcinoma (PDAC) progression, coupled with the lack of effective immunotherapy, underscores the imperative to deepen our understanding of its mechanisms and identify suitable immune ...
Weihui Guo, Zhenyuan Qian, Lei Wang, Weilang Xu, Yuxin Weng, Kai Jiang, Zaiyuan Ye, Ji Xu, Guangyuan Song   +8 more
wiley   +1 more source

Ultraviolet Irradiation Induces c-fos but Not c-Ha-ras Proto-Oncogene Expression in Human Epidermis [PDF]

, 1994
The link between sun exposure and skin cancer is well established, but the mechanism of photocarcinogenesis is still incompletely understood. In vitro experimentation has shown that induction of the c-fos proto-oncogene occurs in cultured human ...
Roddey, Patricia K., Park, Hee-Young, Garmyn, Marjan, Bhawan, J.a.g., Gilchrest, Barbara A.   +4 more
core   +1 more source