Results 31 to 40 of about 35,717 (218)
BMEMat, EarlyView.This study develops a nano‐enzyme patch (ezPatch) targeting bone interfaces. Utilizing ligand‐to‐metal charge transfer (LMCT) catalysis and bone‐targeting ligands on copper nanosheets, ezPatch simultaneously scavenges reactive oxygen species (ROS) and generates oxygen in situ at bone‐losing sites.
Yi Chen +12 more
wiley +1 more source
Signaling through CD44 affects cell cycle progression and c-Jun expression in acute myeloid leukemia cells [PDF]
, 2004 We present here the first evidence linking CD44 signaling to c-Jun expression and cell cycle progression in myeloid cell line models. CD44 ligation with the anti-CD44 monoclonal antibodies have been shown to induce differentiation and inhibit the ...
Abdul Ali Peer Zada +1 more
core
Iranian Journal of Medical Sciences, 2014 Background:Amylin and Salmon Calcitonin belong to the calcitonin family of peptides and have high affinity binding sites in the rat spinal cord. The aim of this study was to characterize receptors for Amylin and Salmon Calcitonin functionally in the ...
Zahra Khoshdel +2 more
doaj
A FOS protein is present in a complex that binds a negative regulator of MYC. [PDF]
, 1989 Regulation of the human proto-oncogene MYC apparently plays an important role in cellular proliferation and the genesis of diverse tumors. Transcription from MYC is governed principally by two promoters known as P1 and P2.
Hay, Nissim +2 more
core +1 more source
Chinese Journal of Contemporary Neurology and Neurosurgery, 2014 Objective To observe the effect of Yangxueqingnao granules on c-Fos protein expression in trigeminal nucleus caudalis (TNC) of nitroglycerin-induced migraine rats.
Xiao-feng LEI +3 more
doaj
Studies of the Transcriptional Control of the Human c-fos Proto-Oncogene [PDF]
, 1989 The c-fos gene is the cellular counterpart of the transforming genes of several retroviruses. Its transcription and expression is increased in many types of different cells following extra-cellular stimuli, and this increase is both rapid and transient ...
Morgan, Iain Matthew
core
Intracellular mediators of c-fos induction
, 1988 Transcription of the c-fos proto-oncogene is rapidly and transiently induced in cells exposed to a remarkably wide range of external stimuli, including growth and differentiation factors, neurotransmitters, drugs, and mechanical stimuli (for review, see ...
Gilman, M. Z. +13 more
core +1 more source
Jak-STAT signaling in liver disease and repair : a way of living [PDF]
, 2005 Signaling through the Jak-STAT pathway is initiated when an extracellular signaling protein binds to its corresponding transmembrane receptor. This leads to activation of the Jaks.
Stutvoet, Simone Tjitske Dorothea
core +1 more source
Precision Medical Sciences, EarlyView.This integrated systems biology study of 2847 exposure‐related genes identifies a conserved 647‐gene core and CYP1B1 hub across cigarette smoke, ozone, and PM2.5. Three key pathways converge, enabling computational repurposing of 15 drug candidates (e.g., NRF2 activators) for environmentally induced COPD.
Fakher Rahim +2 more
wiley +1 more source
Cell Proliferation, EarlyView.Hepatocyte TrkB is identified as a critical gatekeeper against MASH‐related fibrosis. Mechanistically, TrkB inhibits the TGFβ/SMAD3/FOS axis to suppress CCL2 secretion, thereby blocking pathogenic macrophage recruitment and ameliorating liver fibrosis.
Yueying Chen +11 more
wiley +1 more source