Nutraceutical Potential of Anthocyanins: A Comprehensive Treatise
Anthocyanins reduce LDL, VLDL, TGs, and TC via improved GBA and upregulation of ATP6 V0C, ZO‐1, and ATG4D expression. The WHO/FAO suggested that 2.5 mg/kg/day of grape‐skin extracts of anthocyanins is safe, and China recommended that 50 mg/day of anthocyanins is safe for consumption.
Ahmad Mujtaba Noman+12 more
wiley +1 more source
Anthocyanins: From Natural Colorants to Potent Anticancer Agents
Anthocyanin bioavailability has a significant contribution to imposing therapeutic effects on abnormal cells. Anthocyanins hinder cell migration, invasion, and proliferation by inducing apoptosis, suppressing the cell cycle at G0/G1, S, or G2/M stages, and modulating oxidative stress and signaling pathways such as apoptotic cascades, PI3K/Akt, MAPK ...
Muhammad Maaz+13 more
wiley +1 more source
Effects of the N-RAS oncogene on differentiation of CO25 myoblast cells [PDF]
Tez (Doktora) - University of East AngliaAnadolu Üniversitesi, Fen Bilimleri Enstitüsü, Biyoloji Anabilim DalıKayıt no: 19001Effects of a mutant N-ras oncogene (under transcriptional control of the glucocorticoid- inducible MMTV-LTR promotor) on the ...
Zeytinoğlu, Hülya
core
Interaction Between AP-1 Proteins and Glucocorticoid Receptors in Regulation of Lymphokine Activated Killer (LAK) Cell Activity in the Equine Species. [PDF]
This project was performed in order to determine whether exercise-induced increases in plasma cortisol concentrations may be responsible for enhanced lymphokine activated killer (LAK) cell activity.
Bu, Jing
core +2 more sources
Koštana pregradnja pomoću osteoklasta: što smo naučili iz ispitivanja knockout gena? [PDF]
Osteopetroses are disorders of bone remodeling resulting in increased bone mass. Osteopetrosis abnormalities can include changes in osteoclast lineage, bone marrow microenvironment, or both. Little is known about the mechanisms that regulate the activity
Martina Bašić-Koretić+1 more
core +1 more source
c-Jun Proto-Oncoprotein Plays a Protective Role in Lung Epithelial Cells Exposed to Staphylococcal α-toxin [PDF]
c-Jun is a member of the early mammalian transcriptional regulators belonging to the AP-1 family, which participates in a wide range of cellular processes such as proliferation, apoptosis, tumorigenesis, and differentiation.
Andreoli, Veronica+7 more
core +2 more sources
Develop machine learning based predictive models for engineering protein solubility [PDF]
Protein activity is a significant characteristic for recombinant proteins which can be used as biocatalysts. High activity of proteins reduces the cost of biocatalysts. A model that can predict protein activity from amino acid sequence is highly desired, as it aids experimental improvement of proteins.
arxiv
Gonadotropin and kisspeptin gene expression, but not GnRH, are impaired in cFOS deficient mice. [PDF]
cFOS is a pleiotropic transcription factor, which binds to the AP1 site in the promoter of target genes. In the pituitary gonadotropes, cFOS mediates induction of FSHβ and GnRH receptor genes.
Coss, Djurdjica+3 more
core +1 more source
The deazaguanine‐derivative, queuine, affects cell proliferation, protein phosphorylation and the expression of the proto oncogenes c‐fos and c‐myc in HeLa cells [PDF]
Werner Langgut, H. Kersten
openalex +1 more source
A Preliminary Work on Evolutionary Identification of Protein Variants and New Proteins on Grids [PDF]
Protein identification is one of the major task of Proteomics researchers. Protein identification could be resumed by searching the best match between an experimental mass spectrum and proteins from a database. Nevertheless this approach can not be used to identify new proteins or protein variants.
arxiv